Results 31 to 40 of about 447,527 (308)

Multivariate Frequency-Severity Regression Models in Insurance

open access: yesRisks, 2016
In insurance and related industries including healthcare, it is common to have several outcome measures that the analyst wishes to understand using explanatory variables. For example, in automobile insurance, an accident may result in payments for damage
Edward W. Frees, Gee Lee, Lu Yang
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Claim Watching and Individual Claims Reserving Using Classification and Regression Trees

open access: yesRisks, 2019
We present an approach to individual claims reserving and claim watching in general insurance based on classification and regression trees (CART). We propose a compound model consisting of a frequency section, for the prediction of events concerning ...
Massimo De Felice, Franco Moriconi
doaj   +1 more source

Frequency and Severity Dependence in the Collective Risk Model: An Approach Based on Sarmanov Distribution

open access: yesMathematics, 2020
In actuarial mathematics, the claims of an insurance portfolio are often modeled using the collective risk model, which consists of a random number of claims of independent, identically distributed (i.i.d.) random variables (r.v.s) that represent cost ...
Catalina Bolancé, Raluca Vernic
doaj   +1 more source

The Comparison of the Theory of "the Difference between Existential Truths" in Peripatetic Philosophy with the Theory of "the Unity of the Truth of Existence and the Differences of its Levels" in the Transcendental Wisdom [PDF]

open access: yesحکمت صدرایی, 2019
Mulla Sadra has claimed in some of his writings that there is no difference between the unity of the existence and the difference of it in the transcendentalist wisdom, with the theory of difference of existential truths in the peripatetic philosophy ...
Alireza Farsinezhad, Omid Arjomand
doaj   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin   +2 more
wiley   +1 more source

Ruin Probability Functions and Severity of Ruin as a Statistical Decision Problem

open access: yesRisks, 2019
It is known that the classical ruin function under exponential claim-size distribution depends on two parameters, which are referred to as the mean claim size and the relative security loading. These parameters are assumed to be unknown and random, thus,
Emilio Gómez-Déniz   +2 more
doaj   +1 more source

Classification of road traffic injury collision characteristics using text mining analysis: Implications for road injury prevention.

open access: yesPLoS ONE, 2021
Road traffic injuries are a leading cause of morbidity and mortality globally. Understanding circumstances leading to road traffic injury is crucial to improve road safety, and implement countermeasures to reduce the incidence and severity of road trauma.
Melita J Giummarra   +2 more
doaj   +1 more source

A Scoping Review on Artificial Intelligence–Supported Interventions for Nonpharmacologic Management of Chronic Rheumatic Diseases

open access: yesArthritis Care &Research, EarlyView.
This review summarizes artificial intelligence (AI)‐supported nonpharmacological interventions for adults with chronic rheumatic diseases, detailing their components, purpose, and current evidence base. We searched Embase, PubMed, Cochrane, and Scopus databases for studies describing AI‐supported interventions for adults with chronic rheumatic diseases.
Nirali Shah   +5 more
wiley   +1 more source

Inferring disease severity in rheumatoid arthritis using predictive modeling in administrative claims databases.

open access: yesPLoS ONE, 2019
BackgroundConfounding by disease severity is an issue in pharmacoepidemiology studies of rheumatoid arthritis (RA), due to channeling of sicker patients to certain therapies.
Urmila Chandran   +3 more
doaj   +1 more source

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