Results 41 to 50 of about 3,939,616 (339)
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Swiss Medical Weekly, 2019 BACKGROUND To date, comprehensive data on drug utilisation in Swiss nursing homes are lacking. OBJECTIVE To describe drug prescription patterns, polypharmacy and potentially inappropriate medication ...
Rahel Schneider +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Analysis of Evidence on Potential Migration from Bulgaria and Romania [PDF]
, 2013 A collection of sources and data challenging claims of high Romanian and Bulgarian migration into the ...
core
On Invariance and Selectivity in Representation Learning [PDF]
, 2015 We discuss data representation which can be learned automatically from data, are invariant to transformations, and at the same time selective, in the sense that two points have the same representation only if they are one the transformation of the other.
Anselmi, Fabio +2 more
core +3 more sources
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez +12 more
wiley +1 more source
Experimental economics: science or what? [PDF]
, 2007 Do we want experimental economics to evolve into a genuine science? This paper uses the literature on inequity aversion as a case study in warning that we are at risk of losing the respect of other scientific disciplines if we continue to accept the ...
Binmore, K., Shaked, A.
core
Lognormal Model for Insurance Claims Data
Revstat Statistical Journal, 2006 REVSTAT-Statistical Journal, Vol. 4 No.
Daiane Aparecida Zuanetti +2 more
openaire +2 more sources
Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin +2 more
wiley +1 more source