Beyond Tanimoto: a learned bioactivity similarity index enhances ligand discovery [PDF]
Structural similarity metrics such as the Tanimoto coefficient (TC) miss many functionally related compounds—indeed, 60% of similarly bioactive ligand pairs in the ChEMBL database show TC < 0.30, revealing a major blind spot that constrains ligand ...
Gustavo Schottlender +6 more
doaj +2 more sources
Cause Analysis and Solutions About Abnormal Heating of Equipment Clamp [PDF]
As a kind of link terminal in power grid system, clamp has become one of the key components and widely used for connecting the transmission lines and electrical equipment.
Zheng Jianjun, Xu Zhehao, Gong Weiwei
doaj +1 more source
Improving APT Systems’ Performance in Air via Impedance Matching and 3D-Printed Clamp
This paper presents a study on improving the performance of the acoustic piezoelectric transducer system in air, as the low acoustic impedance of air leads to suboptimal system performance.
Liu Liu, Waleed Abdulla
doaj +1 more source
Clamp Nonlinear Modeling and Hysteresis Model Parameter Identification
Based on the Bouc-Wen model, a nonlinear hysteretic restoring force model is established with dynamic equations. The hardening and softening of the material after reaching the yield limit are described by the nonlinear restoring force-displacement ...
Junzhe Lin +5 more
doaj +1 more source
Background Components of metabolic syndrome can be observed in patients with primary hyperparathyroidism (PHPT). The link between these disorders remains unclear due to the lack of relevant experimental models and the heterogeneity of examined groups ...
Ekaterina E. Bibik +10 more
doaj +1 more source
An Analysis of the Vibration Characteristics of an Aviation Hydraulic Pipeline with a Clamp
Taking an aviation hydraulic pipeline as the research object, a fluid–solid coupling vibration model of the pipeline system, considering the influence of the clamp, is established.
Yong Liu +4 more
doaj +1 more source
Junction Properties Interpretation of Textile Geogrids Using Multi-Junction Clamp
In this paper, multi-junction clamp was used for junction strength evaluation under 20, 50 and 100 mm/min of strain rate at ambient condition. One~eight rib specimens were gripped in the clamps and each gage length was 50 mm, 100 mm and 150 mm ...
Aram Lee +4 more
doaj +1 more source
Performing Dual Glucose Clamp Experiments in Sedated Farm Swine: A Practical Method. [PDF]
Torjman MC +4 more
europepmc +3 more sources
A platform technology for generating subunit vaccines against diverse viral pathogens
The COVID-19 pandemic response has shown how vaccine platform technologies can be used to rapidly and effectively counteract a novel emerging infectious disease.
Andrew Young +28 more
doaj +1 more source
Research on maintenance tools of wire clamps for live working on Ultra High Voltage transmission lines [PDF]
Aiming at the problem that the suspension clamp is difficult to be quickly replaced due to the heavy load of the suspension clamp when replacing the transmission line wire suspension clamp in the UHV live operation, this paper develops an auxiliary ...
Wang Zhigang +5 more
doaj +1 more source

