Results 21 to 30 of about 464,001 (296)

Biomechanical comparison of the non-locking bone plate, locking bone plate, and double-rod clamp internal fixation in a canine femoral model [PDF]

open access: yesVeterinary World
Background and Aim: Canine femoral fractures are prevalent in veterinary medicine, necessitating effective fixation methods to ensure stability and promote healing.
Rutjathorn Maneewan   +3 more
doaj   +1 more source

A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of Ik1 Ion Channels in Real-Time

open access: yesFrontiers in Physiology, 2018
An important aspect of the Comprehensive In Vitro Proarrhythmia Assay (CiPA) proposal is the use of human stem cell-derived cardiomyocytes and the confirmation of their predictive power in drug safety assays.
B. Goversen   +7 more
semanticscholar   +1 more source

Comparison of Perioperative, Renal Functional, and Oncological Outcomes Between Off-Clamp and On-Clamp Robot-Assisted Partial Nephrectomy for Renal Tumors: An Updated Evidence-Based Analysis

open access: yesFrontiers in Oncology, 2021
ObjectivesWe aimed to report the latest and largest pooled analysis and evidence update to compare the perioperative, renal functional, and oncological outcomes between off-clamp and on-clamp robot-assisted partial nephrectomy (RAPN) for renal tumors ...
Yin Huang   +12 more
doaj   +1 more source

Triglyceride glucose index as a surrogate measure of insulin sensitivity in obese adolescents with normoglycemia, prediabetes, and type 2 diabetes mellitus: comparison with the hyperinsulinemic–euglycemic clamp

open access: yesPediatric Diabetes, 2016
There is a need for simple surrogate estimates of insulin sensitivity in epidemiological studies of obese youth because the hyperinsulinemic–euglycemic clamp is not feasible on a large scale.
Noor Shafina Mohd Nor   +4 more
semanticscholar   +1 more source

Early Miocene palaeoclimatic reconstruction of Tunçbilek basin

open access: yesTurkish Journal of Forestry, 2019
The Tunçbilek-Domaniç Basin (Western Anatolia) is one of the most important Neogene coal deposits of Turkey. The age of the basin is early Miocene (~ 23-19 Ma) based on dating of volcanic units by the Ar/Ar method.
Hüseyin Tuncay Güner
doaj   +1 more source

Mechanism of opening a sliding clamp

open access: yesNucleic Acids Research, 2017
Clamp loaders load ring-shaped sliding clamps onto DNA where the clamps serve as processivity factors for DNA polymerases. In the first stage of clamp loading, clamp loaders bind and stabilize clamps in an open conformation, and in the second stage ...
Lauren G. Douma   +4 more
semanticscholar   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Aeropuerto Heathrow - Londres (Inglaterra): Nuevo edificio de aduanas

open access: yesInformes de la Construccion, 1970
Diseñado según un módulo cuadrado de 1,524 m de lado, mide 60,96 m de longitud por 36,58 m de anchura. La planta baja alberga: el vestíbulo principal de entrada al público, el «almacén de la reina», el archivo central de documentos y oficinas anejas ...
Arquitectos Manning y Clamp
doaj   +1 more source

Home - About - Disclaimer - Privacy