Results 41 to 50 of about 464,001 (296)

Microstructural Evolution and Mechanical Performance of Plasma‐Assisted Hybrid Friction Stir Welded Dissimilar Aluminum–Copper Joints

Advanced Engineering Materials, EarlyView.
Plasma‐assisted hybrid friction stir welding of dissimilar AlCu joints employs localized plasma preheating to balance heat input and enhance plastic flow. The optimized process reduces axial force by up to 35%, refines the microstructure, and achieves ≈96% joint efficiency.
Deepak Kumar Yaduwanshi, Pankaj Shrivastava, Ganesh Chouhan, Velaphi Msomi   +3 more
wiley   +1 more source

There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments

Frontiers in Molecular Neuroscience, 2022
Fluoride has been used in the internal recording solution for manual and automated patch clamp experiments for decades because it helps to improve the seal resistance and promotes longer lasting recordings.
Markus Rapedius, Alison Obergrussberger, Edward S. A. Humphries, Stephanie Scholz, Ilka Rinke-Weiss, Tom A. Goetze, Nina Brinkwirth, Maria Giustina Rotordam, Tim Strassmaier, Aaron Randolph, Søren Friis, Aiste Liutkute, Aiste Liutkute, Aiste Liutkute, Fitzwilliam Seibertz, Fitzwilliam Seibertz, Fitzwilliam Seibertz, Niels Voigt, Niels Voigt, Niels Voigt, Niels Fertig   +20 more
doaj   +1 more source

Characteristics and physiological basis of falls in ventricular outputs after immediate cord clamping at delivery in preterm fetal lambs [PDF]

, 2021
Joseph J. Smolich, Kelly R. Kenna, Sarah Phillips, Jonathan P. Mynard, Michael Cheung, Gavin Lambert   +5 more
openalex   +1 more source

cryo-EM structures of the E. coli replicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease and τ

eLife, 2015
The replicative DNA polymerase PolIIIα from Escherichia coli is a uniquely fast and processive enzyme. For its activity it relies on the DNA sliding clamp β, the proofreading exonuclease ε and the C-terminal domain of the clamp loader subunit τ.
R. Fernández-Leiro, J. Conrad, S. Scheres, M. Lamers   +3 more
semanticscholar   +1 more source

Dual‐Mode Film Based on Highly Scattering Nanofibers and Upcycled Chips‐Bags for Year‐Round Thermal Management

Advanced Functional Materials, EarlyView.
Intelligent radiative cooling devices, adaptable to various weather conditions, have the potential for year‐round energy savings. This study introduces a sustainable dual‐mode film made from polycaprolactone nanofibers and upcycled chip bags for effective thermal management.
Qimeng Song, Stefan Rettinger, Chengzhang Xu, Ulrich Mansfeld, Markus Retsch   +4 more
wiley   +1 more source

The claudin-like apicomplexan microneme protein is required for gliding motility and infectivity of Plasmodium sporozoites.

PLoS Pathogens, 2023
Invasion of host cells by apicomplexan parasites such as Toxoplasma and Plasmodium spp requires the sequential secretion of the parasite apical organelles, the micronemes and the rhoptries.
Manon Loubens, Carine Marinach, Clara-Eva Paquereau, Soumia Hamada, Bénédicte Hoareau-Coudert, David Akbar, Jean-François Franetich, Olivier Silvie   +7 more
doaj   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

The sliding clamp tethers the endonuclease domain of MutL to DNA

Nucleic Acids Research, 2015
The sliding clamp enhances polymerase processivity and coordinates DNA replication with other critical DNA processing events including translesion synthesis, Okazaki fragment maturation and DNA repair.
M. Pillon, V. M. Babu, Justin R Randall, Jiudou Cai, Lyle A. Simmons, M. Sutton, A. Guarné   +6 more
semanticscholar   +1 more source

Photocatalytic Versus Stoichiometric Hydrogen Generation Using Mesoporous Silicon Catalysts: The Complex Role of Sacrificial Reagents

Advanced Functional Materials, EarlyView.
This study highlights the importance of accounting for stoichiometric hydrogen produced when utilizing Si photocatalysts. The stoichiometric contribution is sacrificial reagent dependent and decreases with increasing sterics around the catalyst surface.
Sarrah H. Putwa, Sarah A. Martell, Berthold Reis, Simona Schwarz, Mita Dasog   +4 more
wiley   +1 more source

Clamp loader ATPases and the evolution of DNA replication machinery

BMC Biology, 2012
Clamp loaders are pentameric ATPases of the AAA+ family that operate to ensure processive DNA replication. They do so by loading onto DNA the ring-shaped sliding clamps that tether the polymerase to the DNA.
Kelch Brian A, Makino Debora L, O'Donnell Mike, Kuriyan John   +3 more
doaj   +1 more source