Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu +13 more
wiley +1 more source
A sandwich‐structured aramid composite paper was designed to integrate high corona resistance and thermal conductivity. The fluorinated graphene/aramid surface layers effectively dissipate space charges to suppress corona discharge. Meanwhile, the boron nitride nanotube/aramid core layer constructs continuous heat‐conduction pathways.
Jun‐Wen Ren +10 more
wiley +1 more source
A Robust Bio‐Supportive Hydrogel Patch for Full‐Thickness Repair of Gastroesophageal Defects
Gastroesophageal defect repair remains a formidable clinical challenge plagued by high leakage and life‐threatening complications. We develop a double‐disc, highly crystalline PVA‐based RBS hydrogel patch featuring suture‐free sealing, robust acid/enzyme resistance and mechanical durability.
Xingqi Song +13 more
wiley +1 more source
Titanium Base-Free Multi-Unit Abutment Connections: A Critical Review of Prosthetic Screw Design, Biomechanical Behavior, and Clinical Performance. [PDF]
Mosaddad SA +5 more
europepmc +1 more source
Carotid-carotid bypass with novel bilateral extracorporeal carotid shunting: A hybrid open and endovascular technique. [PDF]
Siada K +4 more
europepmc +1 more source
Establishment of recurrent laryngeal nerve injury animal models using intraoperative neural monitoring: SD rat models. [PDF]
Gao Y, Li H, Wang T, Zhao Y, Li S.
europepmc +1 more source
A novel clip-based nerve compression model with high stability and reproducibility for the study of chronic nerve injury associated with neuropathic pain. [PDF]
Guo Z +13 more
europepmc +1 more source
Evaluation of a novel strap fixation method for biomechanical testing of sheep Achilles tendons. [PDF]
Basci O +3 more
europepmc +1 more source

