Results 101 to 110 of about 1,240,744 (292)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Theory of noise suppression in {\Lambda}-type quantum memories by means of a cavity

, 2016
Quantum memories, capable of storing single photons or other quantum states of light, to be retrieved on-demand, offer a route to large-scale quantum information processing with light.
Brecht, B., Feizpour, A., Kaczmarek, K. T., Ledingham, P. M., Munns, J. H. D., Nunn, J., Poem, E., Qiu, C., Raymer, M. G., Reddy, Dileep V., Saunders, D. J., Thomas, S., Walmsley, I. A.   +12 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Correction: Layout optimization of irregular storage areas under class storage strategy based on clustering and multi-bin size packing problem.

PLoS ONE
[This corrects the article DOI: 10.1371/journal.pone.0307218.].
Wenbin Zhang, Yuejun Jin, Huarong Zhang, Yiming Wang   +3 more
doaj   +1 more source

Efficient management of backtracking in and-parallelism

, 1986
A backtracking algorithm for AND-Parallelism and its implementation at the Abstract Machine level are presented: first, a class of AND-Parallelism models based on goal independence is defined, and a generalized version of Restricted AND-Parallelism (RAP)
Hermenegildo, Manuel V., Nasr, Roger I.
core  

On the Existence of Optimal Exact-Repair MDS Codes for Distributed Storage [PDF]

, 2010
The high repair cost of (n,k) Maximum Distance Separable (MDS) erasure codes has recently motivated a new class of codes, called Regenerating Codes, that optimally trade off storage cost for repair bandwidth.
Changho Suh, Changho Suh, Kannan Ramch, Kannan Ramchandran   +3 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

On the Determinations of Class-Based Storage Assignments in AS/RS having two I/O Locations [PDF]

This paper presents the use and extension of a geometrical-based algorithmic approach for determining the expected S/R machine cycle times, and therefore warehouse throughput, for class-based storage assignment layouts in an AS/RS.The approach was ...
Ashayeri, J., Beekhof, M., Heuts, R.M.J., Wilhelm, M.R.   +3 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Big data storage management based on new storage

大数据, 2017
How to efficiently store big data and support real-time big data processing and analysis has been the most critical issue in the development of big data technologies.Recently,new storage media such as phase change memory and flash memory provides new ...
Peiquan JIN
doaj