Results 221 to 230 of about 36,491,622 (296)

Hepatitis C viral variants bear signatures of de novo CD8+ T cell and antibody pressure after spontaneous postpartum viral suppression. [PDF]

Proc Natl Acad Sci U S A
Phelps CC, Smith S, Gridley J, Kohout JA, Xu Z, Marcotrigiano J, Rood K, Skinner NE, Grakoui A, Honegger JR, Walker CM.   +10 more
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

GLP-1 Receptor Agonist and Bariatric Surgery Utilization Among Adolescents and Young Adults.

JAMA Pediatr
Messiah SE, Ernest DK, Elnakieb Y, Jang S, Francis JM, Mathew MS, Xie L, Cartwright BR, Qureshi FG, Almandoz JP, Barlow SE.   +10 more
europepmc   +1 more source

Differential methanogenic archaea-induced TLR8-dependent signaling engages gene classes regulated by NF-κB p65 and STAT1/2. [PDF]

Nat Commun
Xu F, Sieverding J, Zhou P, Sah S, Weinberger V, Moissl-Eichinger C, Wohlers I, Heine H.   +7 more
europepmc   +1 more source

Dissociation Between Symptom Burden and Structural Pathology in Patients Undergoing Upper Gastrointestinal Endoscopy: A Retrospective Single-Center Study Using Latent Class Analysis. [PDF]

Medicina (Kaunas)
Grantiņa L, Nagle E, Zolovs M, Dosone D, Sjomina O, Ražuka-Ebela D, Petrošina E, Perevožčikova J, Zolova A.   +8 more
europepmc   +1 more source

Association between latent classes of tobacco, e-cigarette, alcohol, and illicit drug use patterns and depression among Thai adolescents. [PDF]

Addict Behav Rep
Sagayanathan R, Wichaidit W, Stafström M.   +2 more
europepmc   +1 more source

Prognostic Value of Conventional Echocardiographic Parameters of Right Ventricular Dysfunction in a Real-World Cohort of Patients With Acute Pulmonary Embolism. [PDF]

Cureus
Bhagwati M, Mehrotra R, Yaduvanshi A, Kataria V, Bhargava M, Talwar KK, Shah P, Kumar P, Abhishek K.   +8 more
europepmc   +1 more source

Patterns of perceptions and beliefs about PrEP and their association with daily oral PrEP initiation among sexual and gender diverse adolescents in Brazil. [PDF]

Cad Saude Publica
Seixas S, Galvão N, Leite BO, Soares F, Amorim LDAF, Pinto Junior JA, Zucchi EM, Greco DB, Grangeiro A, Dourado I, Magno L.   +10 more
europepmc   +1 more source