Results 151 to 160 of about 35,050,332 (303)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
This paper reports further development of the so-called 1D Lyapunov equation based approach to the stability analysis of differential linear repetitive processes which are a distinct class of 2D continuous-discrete linear systems of both practical and ...
Owens, D H, Rogers, E
core
Class E sortase SrtE and two SrtE-dependent cell wall-anchored hydrophobic proteins are involved in morphogenesis in <i>Actinoplanes missouriensis</i>: occurrence of exploratory growth beyond genus <i>Streptomyces</i>. [PDF]
Tan Z +6 more
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Patient Perceived Quality of Virtual Group Contraception Counseling
Keemi Ereme,1 Kaidee Akullo,2 Quetzal A Class,2 Erica Hinz2 1Obstetrics and Gynecology, University of Washington, Seattle, WA, USA; 2Obstetrics and Gynecology, University of Illinois-Chicago, Chicago, IL, USACorrespondence: Keemi Ereme, University of ...
Ereme K, Akullo K, Class QA, Hinz E
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Estimating the Middle Class in Pakistan [PDF]
The concept ‘middle class’ is one of the most commonly used terms in the social sciences, including economics, sociology and political science. Despite its frequent use there is, however, no consensus on what the term exactly implies and its meaning ...
Durr-e-Nayab
core
Introduction to the Symposium: How Will Artificial Intelligence Affect International Law?
Ashley Deeks
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

