Results 121 to 130 of about 34,288,255 (200)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Investigating the Bounds of Quality Factor for Class-E Series-Tuned RF Power Amplifiers and Their Computer-Aided Optimization

open access: yesApplied Sciences
This paper presents a comprehensive analysis of Class-E series-tuned radio-frequency power amplifiers (RFPAs), focusing on their design and optimization for high efficiency and performance. However, achieving optimal performance involves navigating trade-
Pallab Kr Gogoi   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The ... report of the secretary of the Class of 1862 of Harvard College.

open access: yes
"Printed for the use of the class."Description based on: 3rd (June 1875).Mode of access ...
Harvard College (1780- ). Class of 1862.
core  

Design methodology and characteristics of a class E autogenerator

open access: yesТехнологія та конструювання в електронній апаратурі, 2002
An autogenerator with an output power of 1 W and an efficiency of 86% at a frequency of 800 kHz is calculated and experimentally investigated. A specific feature of the autogenerator is its low supply voltage and weak dependence of the generation ...
V. H. Kryzhanovskyi   +2 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Control Theory for a Class of 2D Continuous-Discrete Linear Systems

open access: yes, 2004
This paper considers a general class of 2D continuous-discrete linear systems of both systems theoretic and applications interest. The focus is on the development of a comprehensive control systems theory for members of this class in a unified manner ...
Owens, D H   +4 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The senior class book of the Class of \u27Ninety-Six, 1896

open access: yes, 1896
The senior class book of the Class of \u27Ninety-Six. South Bethlehem, Pa., 1896. 229 p. : ill., port.

core  

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