Results 151 to 160 of about 35,050,332 (303)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Kronecker Product based Stability Tests and Performance Bounds for a Class of 2D Continuous-Discrete Linear Systems

open access: yes, 2002
This paper reports further development of the so-called 1D Lyapunov equation based approach to the stability analysis of differential linear repetitive processes which are a distinct class of 2D continuous-discrete linear systems of both practical and ...
Owens, D H, Rogers, E
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Patient Perceived Quality of Virtual Group Contraception Counseling

open access: yesOpen Access Journal of Contraception
Keemi Ereme,1 Kaidee Akullo,2 Quetzal A Class,2 Erica Hinz2 1Obstetrics and Gynecology, University of Washington, Seattle, WA, USA; 2Obstetrics and Gynecology, University of Illinois-Chicago, Chicago, IL, USACorrespondence: Keemi Ereme, University of ...
Ereme K, Akullo K, Class QA, Hinz E
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Estimating the Middle Class in Pakistan [PDF]

open access: yes
The concept ‘middle class’ is one of the most commonly used terms in the social sciences, including economics, sociology and political science. Despite its frequent use there is, however, no consensus on what the term exactly implies and its meaning ...
Durr-e-Nayab
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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