Results 51 to 60 of about 1,595,967 (267)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Analysis and Design of a Novel Broadband and High-Efficiency Class-E/FJ Power Amplifier [PDF]

open access: yesAUT Journal of Electrical Engineering
This paper presents a novel hybrid Class-E/FJ power amplifier (PA) that integrates Class-E/F PA and Class-J PA to formulate a high-efficiency as well as broadband performance.
Parastoo Rostami   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Classes e práticas sociais [PDF]

open access: yesRevista Brasileira de Ciências Sociais, 2013
Este artigo tem como principal objetivo lidar com um dilema interpretativo no campo da analise de classe e nas ciencias sociais mais amplamente: a analise de classes e util para investigar os padroes de sociabilidade cotidiana? E possivel conectar classe e status?
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Exploratory behavior undergoes genotype–age interactions in a wild bird

open access: yesEcology and Evolution, 2019
Animal personality traits are often heritable and plastic at the same time. Indeed, behaviors that reflect an individual's personality can respond to environmental factors or change with age.
Barbara Class   +2 more
doaj   +1 more source

THE INFLUENCE OF LOGICAL THINKING ON THE ABILITY TO MANIPULATE RHYTHMIC GYMNASTICS APPARATUS IN ELITE ATHLETES [PDF]

open access: yesGeoSport for Society
Rhythmic gymnastics, a distinguished discipline within the Olympic sports family, exemplifies a sophisticated blend of athleticism and artistic expression, categorizing it as a technicalcombinatory sport where precise motor control is paramount.
Anca Maria SABĂU   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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