Results 121 to 130 of about 34,772,816 (303)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
CLASSは学級集団など中規模集団の人間関係を明らかにすることができる分析方法である。CLASSを活用するためには, 分析プロセスにおいて, 複数回統計分析を行い, 図表を作成する必要がある。そのため, 現場の教師など普段統計分析を用いない人とって,CLASSを活用することは難しいかもしれない。そこで, 調査用紙の作成から分析までのプロセスを解説するマニュアルを作成することにした。departmental bulletin ...
藤本, 学 +4 more
core
Design methodology and characteristics of a class E autogenerator
An autogenerator with an output power of 1 W and an efficiency of 86% at a frequency of 800 kHz is calculated and experimentally investigated. A specific feature of the autogenerator is its low supply voltage and weak dependence of the generation ...
V. H. Kryzhanovskyi +2 more
doaj
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Applications of the genetic algorithm optimisation approach in the design of high efficiency microwave class E power amplifiers [PDF]
In this thesis Genetic Algorithm Optimisation Methods (GA) is studied and for the first time used to design high efficiency microwave class E power amplifiers (PAs) and associated load patch antennas.
Lu, Qing
core
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Here is an ephemeral object just made for a collection like this! Mrs. Bollen's Class was at Cottage Hill Elementary School in Grass Valley, CA. This print-on demand book of 56 pages gives two pages to each pupil's fable, with a colored picture on the ...
Mrs. Bollen's Class
core
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Maturation of nitrogenase cofactor-the role of a class E radical SAM methyltransferase NifB. [PDF]
Hu Y, Ribbe MW.
europepmc +1 more source

