Results 101 to 110 of about 34,772,816 (303)
La sconfitta del linguaggio. L'impossibilità di narrare il Male: W ou le souvenir d'enfance
The defeat of language. The impossibility of telling the Evil: W ou le souvenir d'enfance. Georges Perec's novel W ou le souvenir d'enfance is the result of the fight made by the writer to tell the Evil of his life, the blank left by the tragic loss of ...
Matteo Moca
doaj
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Wireless Charging System Using Resonant Inductor in Class E Power Amplifier for Electronics and Sensors. [PDF]
Wen F, Cheng X, Li Q, Ye J.
europepmc +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
O presente trabalho tem por objetivo realizar, primeiramente, uma ligeira introdução da concepção de de carne biopolítica, na medida em que se perpassa por diferentes autores, os quais serão explicitamente perseguidos com o objetivo de sinalizar os substratos através dos quais se fundamenta uma perspectiva ontológica materialista, sendo ela a expressão
openaire +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Optimization Design of Load-Independent Class-E
This paper proposes an analysis and design method for the load-independent class-E$^{2}$ DC-DC converter, which is composed of the load-independent class-E inverter and the load-independent class-E synchronous rectifier.By combining the newly derived ...
Tatsuki Osato, Xiuqin Wei, Hiroo Sekiya
doaj +1 more source

