Results 101 to 110 of about 35,050,332 (303)

La sconfitta del linguaggio. L'impossibilità di narrare il Male: W ou le souvenir d'enfance

open access: yesIm@go. A Journal of the Social Imaginary, 2017
The defeat of language. The impossibility of telling the Evil: W ou le souvenir d'enfance. Georges Perec's novel W ou le souvenir d'enfance is the result of the fight made by the writer to tell the Evil of his life, the blank left by the tragic loss of ...
Matteo Moca
doaj  

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Entre a classe e a multidão

open access: yesRevista Opinião Filosófica, 2021
O presente trabalho tem por objetivo realizar, primeiramente, uma ligeira introdução da concepção de de carne biopolítica, na medida em que se perpassa por diferentes autores, os quais serão explicitamente perseguidos com o objetivo de sinalizar os substratos através dos quais se fundamenta uma perspectiva ontológica materialista, sendo ela a expressão
openaire   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Optimization Design of Load-Independent Class-E$^{2}$ DC-DC Converter With Performance Visualization

open access: yesIEEE Open Journal of Power Electronics
This paper proposes an analysis and design method for the load-independent class-E$^{2}$ DC-DC converter, which is composed of the load-independent class-E inverter and the load-independent class-E synchronous rectifier.By combining the newly derived ...
Tatsuki Osato, Xiuqin Wei, Hiroo Sekiya
doaj   +1 more source

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