We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Response of soil fungal communities to long-term soil mercury pollution. [PDF]
Du J, Li J, Zhang S, Ren Y.
europepmc +1 more source
Long-Term Outcomes of Class III Malocclusion Interception With Maxillary Expansion and Protraction: A 9-Year Follow-Up Case Report. [PDF]
Saldarriaga-Valencia JA +2 more
europepmc +1 more source
Innovative CRISPR/Cas9-Based Strategy for Allele-Specific HLA Peptidome Analysis Using a Pan-HLA Antibody. [PDF]
Cobos-Figueroa L +6 more
europepmc +1 more source
A major histocompatibility complex (MHC) class II molecule that binds the same viral pathogen peptide with both nonamer and decamer core sequences for presentation to T cells. [PDF]
Goryanin A +4 more
europepmc +1 more source
Structural basis of long-range transcription-translation coupling. [PDF]
Wang C +9 more
europepmc +1 more source
Molecular assessment of recombination processing across genetically diverse mouse strains reveals sexually dimorphic determinants of crossover distribution beyond chromosome length. [PDF]
Horan TS +4 more
europepmc +1 more source
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