Results 111 to 120 of about 4,329,135 (307)
Amherst college, class of 1888. Class record and book of the decennial.
, 1899 p ...
Amherst college. Class of 1888.
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 1926 Tomokan is the Rollins College yearbook published by the Senior ...
Rollins College Senior Class
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Double Instance of the Political. Imaginary – affects as rhetorical means and structure
Im@go. A Journal of the Social Imaginary, 2020 Although emotions are linked to irrationality, a number of recent researches have shown emotions are central to political behaviour. While as politics is an emotionally dense sphere of individual and collective action, any fuller comprehension of the ...
Samuel Mateus
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
, 2009 CLASSは学級集団など中規模集団の人間関係を明らかにすることができる分析方法である｡CLASSを活用するためには， 分析プロセスにおいて， 複数回統計分析を行い， 図表を作成する必要がある｡そのため， 現場の教師など普段統計分析を用いない人とって，CLASSを活用することは難しいかもしれない｡そこで， 調査用紙の作成から分析までのプロセスを解説するマニュアルを作成することにした｡departmental bulletin ...
藤本, 学 +4 more
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