Results 201 to 210 of about 2,397,797 (267)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

AI-driven vibration-based event classification in railway switches and crossings. [PDF]

Sci Rep
Amin MA, Najeh T, Ghoul A.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An empirical study of machine learning robustness and scalability for imbalanced tabular clinical data in emergency and critical care. [PDF]

Sci Rep
Brima Y, Atemkeng M.
europepmc   +1 more source

The Semantic Units Framework, a technology-agnostic representational approach to FAIR and CLEAR knowledge infrastructures. [PDF]

Sci Data
Vogt L.
europepmc   +1 more source

Eliciting Nursing Students' Preferred Designs for Pre-Class Preparation in Large-Group Teaching: An Action Research Study. [PDF]

Nurs Rep
Snibsøer AK, Thompson C, Prytz VK.
europepmc   +1 more source

mRNA delivery of a class 1/4 SARS-CoV-2 neutralizing antibody protects against diverse sarbecoviruses in a lethal mouse challenge model. [PDF]

Proc Natl Acad Sci U S A
Skelly AN, Fan C, Keeffe JR, Ökten AB, Gavor E, Newby ML, Allen JD, Kreider EF, Ding W, Osbaldeston RA, Park Y, Connell AJ, Lituchy MG, Bibollet-Ruche F, Radford KM, P West A, Peña-Hernández MA, Cruickshank K, Liu W, Li Y, Albertus A, McWilliams B, Russell RM, Konrath KM, Torres JL, Yuan M, Gao H, Montefiori DC, Saag MS, Goepfert PA, Kulp DW, Ward AB, Wilson IA, Shaw GM, Andrabi R, Crispin M, Weissman D, Wilen CB, Bjorkman PJ, Hahn BH.   +39 more
europepmc   +1 more source

Early Protraction Facemask Followed by Fixed Appliance Therapy in a Growing Patient With Skeletal Class III Malocclusion: A Case Report. [PDF]

Case Rep Dent
Lim AYR, Tey SN, Khan KAM.
europepmc   +1 more source

Relationship between transition shock, psychological contract, and resilience among new graduate nurses: a latent profile analysis. [PDF]

Front Public Health
Chen D, Li Z, Wang L, Fu A, Xia X, Tian T, Zhou W, Hu Y, Chen T.   +8 more
europepmc   +1 more source