Results 231 to 240 of about 10,919,668 (279)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Stereochemical aspects of the nucleophilic attack in different classes of L-asparaginases. [PDF]

IUCrJ
Gilski M, Pokrywka K, Jaskolski M.
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Identifying Latent Classes of Dual Cigarette/ENDS Users Based on Motivations for ENDS Use: Product Substitution Versus Complementary Use. [PDF]

Nicotine Tob Res
Pacek LR, Ganz O, Rubenstein D, Barnwell PV, McClernon FJ.   +4 more
europepmc   +1 more source

Effect of preexisting human leukocyte antigen donor-specific antibodies especially human leukocyte antigen-DQ on kidney transplant outcome. [PDF]

Front Nephrol
Mehrotra S, Sharma RK, Kapoor R, Jaiswal RK, Kapoor R.   +4 more
europepmc   +1 more source

Approval of AI-Based Medical Devices in China From 2020 to 2025: Retrospective Analysis.

JMIR Med Inform
Zhang L, Yan J.
europepmc   +1 more source

Symptom experience subtypes and their association with social isolation in older adults with diabetes and coronary heart disease: a latent profile analysis study. [PDF]

Front Med (Lausanne)
Zhou N, Gu Y, Liu J, Zhang L, Chen L, Lu Y, Peng T.   +6 more
europepmc   +1 more source

Structural Design of T-Cell Epitope-Based mRNA Vaccine Constructs Determines the Quality of T-Cell Immunity and Protective Efficacy Against SARS-CoV-2 in Mice. [PDF]

Vaccines (Basel)
Gushchin VA, Siniavin AE, Pochtovyi AA, Dzharullaeva AS, Shcherbinin DN, Ungur AS, Tukhvatulin AI, Shuliakova IV, Kleymenov DA, Mazunina EP, Bykonia EN, Kozlova SR, Usachev EV, Zorkov ID, Grousova DM, Iliukhina AA, Gintsburg AL, Logunov DY.   +17 more
europepmc   +1 more source

PHA synthase variant design using a conditional variational autoencoder. [PDF]

PLoS Comput Biol
Tenkanen T, Ylinen A, Jouhten P, Penttilä M, Castillo S.   +4 more
europepmc   +1 more source

Comparison of post-treatment complications of conventional composites versus self-adhering composites: a review. [PDF]

Biomater Investig Dent
Farshad F, Eskandari E, Rohaninasab M.
europepmc   +1 more source