Results 101 to 110 of about 3,951,974 (320)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Class Action and Its Role in Consumer Protection Law [PDF]
Faṣlnāmah-i Pizhūhish-i Huqūq-i Khuṣūṣī, 2012 The inefficiency of civil procedure rules, the producers’ high profit andlow value damages suffered by consumers has made legal systems findsome solutions so that justice would be performed at the best.
Hassan MOHSENI +2 more
doaj
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Jurnal Vokasi Indonesia, 2013 This research is motivated by the lack of passionate students of the Program Studi Perumahsakitan Vokasi in the following study courses Biostatistics, because the teaching method does not make the students become active and participate.
Nia Murniati, Supriadi, Tri Gunadi
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Short Run Capability Improvement Efforts Through Varied Learning Approaches
Active: journal of physical education, sport, health and recreation, 2017 The purpose of this research was done to upgrade the learning approach through the short run variable on the students grade 3 son SD N Krebet 3 Masaran Sragen 2015/2016 school year. This research is Class action, research was conducted with two-cycle and
Jasmani
doaj
Resolución de problemas en la enseñanza de la geología: contribuciones de un estudio exploratorio [PDF]
Revista Eureka sobre Enseñanza y Divulgación de las Ciencias, 2007 This research study consisted on the conception, application and evaluation of a teaching planning based in a subject of Natural Sciences (Geology) and through Problem Solving.
Carrasquinho, S. +2 more
doaj
, 1998 Article deposited after permission was granted by the editor of LawNow magazine, 06/28/2010.
openaire +2 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source