Results 191 to 200 of about 3,951,974 (320)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

An integrative head-heart-hands model of moral education: evidence from Chinese higher education. [PDF]

Front Psychol
Wang M, Saharuddin N, Yasin M, Chen X.
europepmc   +1 more source

Allocation Rules and the Stability of Mass Tort Class Actions

, 2010
Joshua C. Teitelbaum
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

DaRA Dataset: Combining Wearable Sensors, Location Tracking, and Process Knowledge for Enhanced Human Activity and Human Context Recognition in Warehousing. [PDF]

Sensors (Basel)
Niemann F, Rueda FM, Al Kfari MK, Nair NR, Schauten D, Kretschmer V, Lüdtke S, Kirchheim A.   +7 more
europepmc   +1 more source

The Agency Class Action

, 2012
Michael Sant'Ambrogio, Adam S. Zimmerman
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

β-Hairpin Antimicrobial Peptides: Class Diversity and Sequence Analysis. [PDF]

ACS Infect Dis
Ramtel R, Gu R, Abdulkareem MA, Randall JR.   +3 more
europepmc   +1 more source

Identifying Ineffective Monitors from Securities Class Action Lawsuits

, 2016
Chishen Wei, Lei Zhang
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source