Results 131 to 140 of about 3,286,986 (287)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Pemanfaatan Media Rangka Aves Dalam Pembelajaran Biologi Untuk Siswa Kelas XI IPA Ma Ali Maksum Pada Submateri Pokok Rangka [PDF]

open access: yes, 2014
This research aimed to investigate the improvement of learning outcomes and student interest at MA Ali Maksum students on skeletal system materials after the media Aves skeletal system was implemented in the class. This research was carried out by using
Susilawati, L. (Lela)
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Meningkatkan Motivasi Dan Pemahaman Konsep Perbandingan Fungsi Trigonometri Melalui Model Pembelajaran Jigsaw Di SMA Negeri 8 Kota Jambi [PDF]

open access: yes, 2012
Classroom action research by applying the Jigsaw learning model was conducted in learning of Mathematics in class X of SMAN 8 Jambi in the second semester of 2012.
Haryani, F. (Fitri)
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Do Mass Tort Negligence Class Actions Adequately Compensate Victims and Effectively Deter Tortfeasor Wrongdoing?

open access: yesLaws
The objectives of the class action procedural device and the tort of negligence overlap in that they both seek to compensate victims for their loss and, according to some, they both seek to deter tortfeasor wrongdoing.
Nikki Chamberlain, Michael Legg
doaj   +1 more source

Peningkatan Keaktifan Siswa Pada Pembelajaran Matematika Melalui Strategi Student Team Achivemet PTK Bagi Siswa Kelas VIIB SMP Islam Ngesrep Tahun 2014/2015 [PDF]

open access: yes, 2016
The research to increase student activity in the learning of mathematics for students of Islamic junior class Ngesrep VIIB 2014/2015 school year through the Student Team Achievement Division strategy. This research is a class act consisting of two cycles,
Susanti, Ika Malina
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Class Actions and the Poor [PDF]

open access: yes, 2007
[Excerpt] “Imagine that you are a legal aid lawyer in America whose services are funded by the Federal Legal Services Corporation (LSC). You interview a prospective client and learn that she was recently laid off from her job; she applied for and was ...
Rose, Henry
core   +2 more sources

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