Results 251 to 260 of about 3,286,986 (287)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Geometric Learning of Canonical Parameterizations of 2D-Curves. [PDF]

Entropy (Basel)
Ciuclea I, Longari G, Tumpach AB.
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

ProTCR: a protein language model-driven framework for decoding TCR-antigen recognition toward precision immunotherapies. [PDF]

Brief Bioinform
Xu M, Lu M, Liu P, Zhang S, Chen L, Liu Q, Lin Y, Xie L.   +7 more
europepmc   +1 more source

Explaining Performance Gaps with Problem-Solving Process Data via Latent Class Mediation Analysis. [PDF]

Psychometrika
Kwon S, Zhang S.
europepmc   +1 more source

Action Research on Improving the Interaction of Middle School Chinese Class

Proceedings of the 5th Annual International Conference on Social Science and Contemporary Humanity Development (SSCHD 2019), 2019
openaire   +1 more source

The IUPHAR/BPS Guide to PHARMACOLOGY in 2026. [PDF]

Nucleic Acids Res
Harding SD, Armstrong JF, Faccenda E, Southan C, Alexander SPH, Davenport AP, Spedding M, Davies JA.   +7 more
europepmc   +1 more source

Active Inference and Functional Parametrisation: Differential Flatness and Smooth Random Realisation. [PDF]

Entropy (Basel)
Mounier H, Parr T, Friston K.
europepmc   +1 more source

Attention to detail: A conditional multi-head transformer for traffic sign recognition. [PDF]

PLoS One
Naz I, Shah JH, Tahir A, Marri MR, Saleem R, Saeed MES.   +5 more
europepmc   +1 more source

A novel adaptive hybrid intrusion detection system with lightweight optimization for enhanced security in internet of medical things. [PDF]

Sci Rep
Saeed H, Naseer M, Rasool A, Alsirhani A, Alserhani F, Alwakid GN, Ullah F, Naeem H, Zhao Y.   +8 more
europepmc   +1 more source