Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
An assessment of antimicrobial resistance national action plans and their impact on antibiotic use. [PDF]
O'Neill E +4 more
europepmc +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Substance-Based Medical Device in Wound Care: Bridging Regulatory Clarity and Therapeutic Innovation. [PDF]
Ianev D +6 more
europepmc +1 more source
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
A dataset of scientific citations in U.S. patent Office Actions. [PDF]
Higham K +4 more
europepmc +1 more source
Action Research on Improving the Interaction of Middle School Chinese Class
openaire +1 more source
Guideline in Action: General Supportive Early Management: Blood Pressure and Glucose. [PDF]
Wang J, Tahsili-Fahadan P.
europepmc +1 more source
Retrospective analysis of U.S. Food and Drug Administration recalls of artificial tear solutions from 2014 to 2025. [PDF]
Bhattacharya A, Kang PC.
europepmc +1 more source
Interpretable crop pest and disease identification based on comparative concept tree. [PDF]
Jia B +5 more
europepmc +1 more source

