Results 91 to 100 of about 2,322,151 (276)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The Long-Awaited Directive on Representative Actions: Still Waiting for Godot…
Revista Ítalo-Española de Derecho Procesal, 2020 On 25 November 2020, the EU adopted the Directive on Representative Actions. This long-awaited legal instrument is the first to create a binding European-wide collective action mechanism for monetary relief.
Csongor István Nagy
doaj
Ri-vista: Ricerche per la Progettazione del Paesaggio, 2015 After its abandoning as an infrastructural axis (transportation and economic) the Loire river middle course starts today a process of valorisation and revitalisation of its cultural and natural landscapes. According to the most recent declinations of the
Laura Verdelli
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Danish class actions - a European model?
International Journal of Private Law, 2012 The authors present the EU intentions to take legislative action in respect of class actions and outline the recent, national initiatives on class actions within the member States of the EU. Then, the main features of US class actions are outlined followed by a detailed examination of the new Danish provisions on class actions.
Nielsen, Peter Arnt, Linhart, Karin
openaire +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A Robust Bayesian Approach to an Optimal Replacement Policy for Gas Pipelines
Entropy, 2015 In the paper, we address Bayesian sensitivity issues when integrating experts’ judgments with available historical data in a case study about strategies for the preventive maintenance of low-pressure cast iron pipelines in an urban gas distribution ...
José Pablo Arias-Nicolás +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The important role of civil class actions in the enforcement of corporate criminal law
Journal of Economic CriminologyRecent experience in civil litigation, particularly with opt-out class actions against corporations for competition law offences, has highlighted the efficiency of ‘dual enforcement’ as a strategy for fighting corporate crime.
Alison Cronin
doaj +1 more source
Distribution of Funds in Class Actions - Claims Administration [PDF]
, 2009 Most class action securities cases result in a settlement where the parties agree on a defined amount of money to be placed in a fund for distribution to eligible beneficiaries.
McGovern, Francis
core +1 more source