Results 231 to 240 of about 2,319,971 (295)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Outcomes and Acceptability of the Community-Based Occupational Well-Being Intervention Among Health Care Educators-Mixed Method Pilot Study. [PDF]

Scand J Caring Sci
Vauhkonen A, Honkalampi K, Rinne J, Salminen L, Saaranen T.   +4 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Glucagon-like Peptide-1 Receptor Agonists and Ocular Disease: Mechanisms, Evidence and Therapeutic Perspectives. [PDF]

Int J Mol Sci
Gong X, Örge FH.
europepmc   +1 more source

Global trends in post-market surveillance of high-risk medical devices: An empirical analysis based on regulatory data. [PDF]

Indian J Med Res
Manimuthukumar O, Manjuladevi M, Arunkumar T.   +2 more
europepmc   +1 more source

Intelligent strength training for football players using resnext optimized by upgraded chimp optimization algorithm. [PDF]

Sci Rep
Zhang W, Zhang Y.
europepmc   +1 more source

The Roles of Incretin Hormones GIP and GLP-1 in Metabolic and Cardiovascular Health: A Comprehensive Review. [PDF]

Int J Mol Sci
Yamanouchi D.
europepmc   +1 more source

Phytochemical small molecules from <i>Stauntonia chinensis</i> DC as multi-target modulators: molecular mechanisms and therapeutic potential. [PDF]

Am J Transl Res
Cheng F, Wang SM, Xiao M, Zhou H, Chen B, Zhang QH.   +5 more
europepmc   +1 more source

Emerging Role of Dual Glucagon-Like Peptide-1 (GLP-1)/Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor Agonists in Cardiovascular Prevention. [PDF]

Cureus
Contreras Figueroa N, Lopez Mendoza MJ, Ulloa A, Jiron Vindas J, Salazar Estrada MA, Valle Mena MJ.   +5 more
europepmc   +1 more source

Class actions

, 2016
openaire   +1 more source