Results 51 to 60 of about 209,106 (263)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
MoleculesDibenzyltoluene (H0-DBT), a Liquid Organic Hydrogen Carrier (LOHC), presents an attractive solution for hydrogen storage due to its enhanced safety and ability to store hydrogen in a concentrated liquid form.
Ahsan Ali +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
DYNAMIC ABC STORAGE POLICY IN ERRATIC DEMAND ENVIRONMENTS
Jurnal Teknik Industri, 2003 The paper describes a dynamic variant of the traditional ABC storage policy. The variant is to be used in manual order picking warehouses where SKUs experience a rather unstable demand. Its objective is to reduce the order picking time.
Benjamin Pierre +3 more
doaj
PLoS ONE, 2014 Accurate estimates of forest carbon storage and changes in storage capacity are critical for scientific assessment of the effects of forest management on the role of forests as carbon sinks. Up to now, several studies reported forest biomass carbon (FBC)
Dapao Yu +9 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Anthropogenic carbon storage and its decadal changes in the Atlantic between 1990–2020 [PDF]
BiogeosciencesThe Atlantic inventory of anthropogenic carbon (Cant) and its changes between 1990 and 2020 are investigated by applying the transit time distribution (TTD) method to anthropogenic tracer data.
R. Steinfeldt +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Analytical model to estimate the performance of shuttle-based storage and retrieval systems with class-based storage policy [PDF]
The International Journal of Advanced Manufacturing Technology, 2020 AbstractThis paper presents a method to determine the performance of shuttle-based storage and retrieval systems (SBS/RS) with tier-captive single-aisle shuttles and class-based storage policy. The use of this approach takes place both in the design process of SBS/RS and in the redesign process of SBS/RS.
openaire +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source