Results 111 to 120 of about 1,263,097 (263)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Addressing the trade off between smells and quality when refactoring class diagrams. [PDF]

open access: diamond, 2021
Angela Barriga   +4 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

ROLE OF UML SEQUENCE DIAGRAM CONSTRUCTS IN OBJECT LIFECYCLE CONCEPT

open access: yesJournal of Information and Organizational Sciences, 2007
When modeling systems and using UML concepts, a real system can be viewed in several ways. The RUP (Rational Unified Process) defines the "4 + 1 view": 1. Logical view (class diagram (CD), object diagram (OD), sequence diagram (SD), collaboration diagram
Miroslav Grgec, Robert Mužar
doaj  

LLM-Driven MDA Pipeline for Generating UML Class Diagrams and Code

open access: yesIEEE Access
The transformation of textual specifications into formal software models is a major challenge in software design automation. This study presents an integrated approach that combines the natural language interpretation capabilities of transformer models ...
Zakaria Babaalla   +2 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

On Implementing Open World Semantic Differencing for Class Diagrams. [PDF]

open access: diamond, 2023
Jan Oliver Ringert   +2 more
openalex   +1 more source

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