Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Efficient and Stable Gas Drainage Technology for the Entire Life Cycle of Boreholes in Soft Coal Seams. [PDF]
ACS OmegaLi B, Yang J, Cui J, Lu P, Wang M, Li Q.
europepmc +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
A moderated multilevel multiple mediation model of the effect of class teacher communication style on adolescents' school adjustment: the roles of basic psychological needs and psychological <i>suzhi</i>. [PDF]
Front PsycholDong S, Wu J.
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Broadband slant-polarized series-fed microstrip patch antenna array based on magnetic current feeding technology. [PDF]
Sci RepZhao Y +6 more
europepmc +1 more source
Verification and validation in systems engineering : application to UML 2.0 activity and class diagrams [PDF]
, 2006 Luay Alawneh
openalex
Automatic Hierarchical Layout Algorithm for UML Class Diagram [PDF]
, 2009 Xiaobo Wang, Huan Wang, Chao Liu
openalex +1 more source