Results 181 to 190 of about 277,211 (244)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Identifying topological phases through global and local symmetries of the quantum transfer matrix. [PDF]

Sci Rep
Oh YT, Lee HY.
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Characterization of the gut microbiota in people with different levels of obesity. [PDF]

Front Microbiol
Li E, Wang S, Li Y, Liuli A, Liang M, Huang J, Li Y, Li H, Feng Z.   +8 more
europepmc   +1 more source

The Role of Class Diagram in Estimating Software Size

, 2012
Mohammad Harizi
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Quantitative ultrasound imaging for predicting response and guiding personalized neoadjuvant chemotherapy in breast cancer: randomized phase 2 clinical trial results. [PDF]

NPJ Precis Oncol
Moore-Palhares D, Alberico D, Chan AW, DiCenzo D, Sannachi L, Dasgupta A, Yip J, Pena MLA, Gandhi S, Pezo R, Eisen A, Jerzak KJ, Gonzalez CAC, Warner E, Wright FC, Look-Hong N, Roberts A, Sadeghi-Naini A, Curpen B, Skarpathiotakis M, Betel C, Kolios MC, Trudeau M, Czarnota GJ.   +23 more
europepmc   +1 more source

van Krevelen diagram of the compound classes associated with the H:C and O:C-coordinate plane and CHO Index plot with N:C coordinate.

, 2015
Mann Benjamin F., Hongmei Chen, Hamdi Ouml z ccedil elik M., Chu Rosalie K., Tolić Nikola, F. Portier Evan, Roy Chowdhury Taniya, Robinson Errol W., Callister Stephen J., Diana Stan, Graham David E., Liang Liyuan, Gu Baohua   +12 more
openalex   +2 more sources

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Surface water quality classification and prediction model based on multiple machine learning algorithms. [PDF]

Sci Rep
Man G, Yun Q, Qilin Z, Yuyong L, Zhuoshi Z.   +4 more
europepmc   +1 more source