Results 61 to 70 of about 2,513,918 (282)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

New T-duality for Chern-Simons theory

Journal of High Energy Physics, 2019
It has recently pointed out that a four-dimensional analog of Chern-Simons theory provides an elegant framework for understanding integrable models with spectral parameters.
Masahito Yamazaki
doaj   +1 more source

6d SCFTs, 5d dualities and Tao web diagrams

Journal of High Energy Physics, 2019
We propose 5d descriptions of 6d N = 1 , 0 $$ \mathcal{N}=\left(1,\ 0\right) $$ superconformal field theories arising from Type IIA brane configurations with an O8−-plane.
Hirotaka Hayashi, Sung-Soo Kim, Kimyeong Lee, Futoshi Yagi   +3 more
doaj   +1 more source

Relativistic action at a distance and fields

, 2011
After a brief review of the field formulations and the relativistic non-instantaneous action-at-a-distance formulations of some well known classical theories, we study Rivacoba's generalization of a theory with a linearly rising potential as a ...
Louis-Martinez, Domingo J.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Scale invariance beyond criticality within the mean-field analysis of tensorial field theories

Journal of High Energy Physics
We continue the series of articles on the application of Landau-Ginzburg mean-field theory to unveil the basic phase structure of tensorial field theories which are characterized by combinatorially non-local interactions.
Roukaya Dekhil, Alexander F. Jercher, Daniele Oriti, Andreas G. A. Pithis   +3 more
doaj   +1 more source

A self-consistent equation of state for nuclear matter [PDF]

, 2006
The authors formulate a phenomenological extension of the mean-field theory approach and define a class of thermodynamically self-consistent equations of state for nuclear matter.
Bugaev, Kyrill A., Gorenstein, Mark I., Greiner, Walter, Rischke, Dirk-Hermann, Stöcker, Horst   +4 more
core  

Oscillating bounce solutions and vacuum tunneling in de Sitter spacetime

, 2004
We study a class of oscillating bounce solutions to the Euclidean field equations for gravity coupled to a scalar field theory with two, possibly degenerate, vacua. In these solutions the scalar field crosses the top of the potential barrier $k>1$ times.
Hackworth, James C., Weinberg, Erick J.
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source