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Emerging perspectives on leveraging physiologically based biopharmaceutics modeling (PBBM) for BCS class III biowaivers: A webinar summary. [PDF]
J Pharm SciFang L +8 more
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2022
Highly conserved from yeast to mammals, vacuolar protein sorting 34 (Vps34) is the sole member of the third class of the phosphoinositide 3-kinase (PI3K) family. By producing phosphatidylinositol-3-monophosphate (PtdIns3P) through its scaffolding function essential for the catalytic lipid activity, Vps34 regulates endosomal trafficking, autophagy ...
Manuella, Caux +2 more
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Highly conserved from yeast to mammals, vacuolar protein sorting 34 (Vps34) is the sole member of the third class of the phosphoinositide 3-kinase (PI3K) family. By producing phosphatidylinositol-3-monophosphate (PtdIns3P) through its scaffolding function essential for the catalytic lipid activity, Vps34 regulates endosomal trafficking, autophagy ...
Manuella, Caux +2 more
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Class III antiarrhythmic drugs
Current Opinion in Cardiology, 1994Pharmacological therapy of cardiac arrhythmias continues to evolve, with an increasing shift from class I to class III compounds and beta-blockers. This is engendered by increasing concern that class I antiarrhythmic drugs might adversely affect mortality in patients with significant structural heart disease.
B N, Singh, R, Ahmed
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2013
Class III peroxidases are heme-containing proteins of the secretory pathway with an extremely high number of isoenzymes, indicating the tremendous and important functions of this protein family. This chapter describes fractionation of the cell in subproteomes, their separation by polyacrylamide gel electrophoresis (PAGE) and visualization of peroxidase
Sabine, Lüthje +5 more
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Class III peroxidases are heme-containing proteins of the secretory pathway with an extremely high number of isoenzymes, indicating the tremendous and important functions of this protein family. This chapter describes fractionation of the cell in subproteomes, their separation by polyacrylamide gel electrophoresis (PAGE) and visualization of peroxidase
Sabine, Lüthje +5 more
openaire +2 more sources
A Class III Antiarrhythmic Agent
American Journal of Critical Care, 2002Scenario: A 72-year-old woman presents to the emergency department with complaints of dizziness. She is currently under the care of a cardiologist for ventricular arrhythmias and admits that she is “a bit confused about her daily dose” of amiodarone. Bedside monitoring is initiated, and the ECG technician is on his way to obtain a 12-lead ECG.
Michele M, Pelter, Mary G, Adams
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Journal of Oral and Maxillofacial Surgery, 1982
Abstract A discussion of the esthetic relationships involved with Class III malocclusion is presented, and a suggested method of treatment is outlined. Three case reports illustrate the syndrome and its correction.
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Abstract A discussion of the esthetic relationships involved with Class III malocclusion is presented, and a suggested method of treatment is outlined. Three case reports illustrate the syndrome and its correction.
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An Unusual Class III Malocclusion
British Journal of Orthodontics, 1986A nine year old caucasian boy presented with bilateral double upper central incisors in Class III relationship. In addition 4 showed an abnormal root morphology and path of eruption. The double teeth were retained and the incisor relationship was corrected orthodontically. Following surgical exposure, 4 erupted favourably.
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2007
The class III myosins are distinguished from other myosin classes by the kinase at their N- terminus, but resemble other myosins in that ahey possess a typical conserved motor domain, a neck domain with IQ motifs and variable tails. Myosin III is expressed predominantly in sensory cells in both invertebrates and vertebrates where it localizes to ...
ANDRÉA DOSÉ +2 more
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The class III myosins are distinguished from other myosin classes by the kinase at their N- terminus, but resemble other myosins in that ahey possess a typical conserved motor domain, a neck domain with IQ motifs and variable tails. Myosin III is expressed predominantly in sensory cells in both invertebrates and vertebrates where it localizes to ...
ANDRÉA DOSÉ +2 more
openaire +1 more source