Results 81 to 90 of about 831,819 (311)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Functional Analysis of Unilateral Cleft-Lip Palate and Skeletal Class III Individuals

Turkish Journal of Orthodontics, 1999
The aim of the current study was to determine and compare mandibular functions of cleft lip and palate (CLP) patients and Angle Class III individuals by using modified ‘Rakosi Functional Analysis’ method.
M. Okan Akçam, Erhan Özdiler, Tunç Altıok, Birol Özel, Ensar Başpınar   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Comparison of Soft Tissue Profile between Subgroups of Skeletal Class III Malocclusion

Turkish Journal of Orthodontics, 2010
Aim:The aim of this study is to compare the soft tissue profiles of patients with skeletal Class III malocclusions originated from; maxillary retrusion, mandibular protrusion and the combination of maxillary retrusion and mandibular protrusion.Material ...
Gökmen Kurt, Ayşe Tuba Altuğ Ataç, Ayça Üstdal   +2 more
doaj   +1 more source

Kidney Biopsy Findings and Management of Kidney Diseases in Patients with Class III Obesity: A Single-Center Experience

Background: Class III obesity, formerly known as morbid obesity, is a known risk factor for chronic kidney diseases. Due to outdated information suggesting that morbid obesity is a contraindication for kidney biopsy and the misconception that proteinuria
Rezzan Eren Sadioğlu, Saba Kiremitçi, Kenan Keven   +2 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Gender-based Comparison of Pharyngeal Airway Between Class I and Class III Patients During MP3cap Growth Period

Turkish Journal of Orthodontics
Objective: To compare the pharyngeal airway size and area between Class III patients exhibiting optimal vertical growth direction and Class I patients at the MP3cap stage, considering gender differences.
Merve Kurnaz, Bülent Çelik, Emine Kaygısız   +2 more
doaj   +1 more source

Dento-Facıal And Soft Tıssue Changes Followıng Sagıtıal Splıt Osteotomı In Class Iıı Malocclusıons

Turkish Journal of Orthodontics, 1995
The study was performed on eleven Class III females with ages ranging from 19 to 23. Following orthodontic preparation sagittal split osteotomi was applied to an patients bilaterally.
Nazan Küçükkeleş, Nejat Erverdi, Tahir Hayırlıoğlu   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source