Results 81 to 90 of about 154,181 (262)

On the Robustness of Compressed Models with Class Imbalance

Computers
Deep learning (DL) models have been deployed in various platforms, including resource-constrained environments such as edge computing, smartphones, and personal devices. Such deployment requires models to have smaller sizes and memory footprints. To this end, many model compression techniques proposed in the literature successfully reduce model sizes ...
Baraa Saeed Ali, Nabil J. Sarhan, Mohammed Alawad   +2 more
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Improving Model Performance for Predicting Exfiltration Attacks Through Resampling Strategies

International Islamic University Malaysia Engineering Journal
Addressing class imbalance is critical in cybersecurity applications, particularly in scenarios like exfiltration detection, where skewed datasets lead to biased predictions and poor generalization for minority classes.
Arif Rahman Hakim, Kalamullah Ramli, Muhammad Salman, Esti Rahmawati Agustina   +3 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

MKC-SMOTE: A Novel Synthetic Oversampling Method for Multi-Class Imbalanced Data Classification

IEEE Access
The learning of multi-class imbalance problems presents greater challenges and has fewer research results compared to binary imbalance problems. Resampling techniques are widely employed to address data imbalance problems.
Jiao Wang, Norhashidah Awang
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

MCH-Ensemble: Minority Class Highlighting Ensemble Method for Class Imbalance in Network Intrusion Detection

Applied Sciences
As cyber threats such as denial-of-service (DoS) attacks continue to rise, network intrusion detection systems (NIDS) have become essential components of cybersecurity defense.
Sumin Oh, Seoyoung Sohn, Chaewon Kim, Minseo Park   +3 more
doaj   +1 more source