Results 11 to 20 of about 1,159 (110)
Arthritis &Rheumatology, EarlyView.Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by IKZF1 haploinsufficiency. Methods Peripheral immune cells from a patient with IKZF1 haploinsufficiency, patients with lupus with no currently known genetic mutations, and healthy controls were analyzed using single‐cell
Qi Zheng +6 more
wiley +1 more source
NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease
Advanced Science, Volume 13, Issue 14, 9 March 2026.NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang +18 more
wiley +1 more source
Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium
Advanced Science, Volume 13, Issue 14, 9 March 2026.This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du +5 more
wiley +1 more source
Advanced Science, Volume 13, Issue 18, 27 March 2026.Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang +12 more
wiley +1 more source
Advanced Science, Volume 13, Issue 10, 18 February 2026.Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao +8 more
wiley +1 more source
Journal of the Association for Information Science and Technology, Volume 77, Issue 1, Page 40-61, January 2026.Abstract This chapter examines the contours of the religious and spiritual information experiences subfield through a review and content analysis of selected contributions from the past two decades in both information science and related fields. The research question that guides this review is: How have spirituality and religion been conceptualized in ...
Nadia Caidi +4 more
wiley +1 more source
Journal of the Association for Information Science and Technology, Volume 77, Issue 1, Page 198-223, January 2026.Abstract The term semantic primitives refers to a set of basic, atomic concepts from which all other (compound) concepts are constructed. It presupposes the principle of compositionality—the idea that complex items or expressions can be formed by combining simpler constituents.
Birger Hjørland
wiley +1 more source
Human Behavior and Emerging Technologies, Volume 2026, Issue 1, 2026.The rapid progression of digital technology, especially artificial intelligence (AI), has catalyzed substantial advancements in e‐commerce. In Vietnam, AI‐integrated e‐commerce platforms are increasingly attracting consumer interest due to their ability to personalize user experiences and enhance service quality.
Nguyen Ngoc Hien +4 more
wiley +1 more source
Human Behavior and Emerging Technologies, Volume 2026, Issue 1, 2026.Rapid digital adoption in Nigeria has been accompanied by rising cybercrime; a 2021 Sophos survey found 71% of Nigerian organizations experienced cyberattacks, 44% of which paid ransoms averaging USD 3.43 million. The integration of emerging technologies (artificial intelligence, blockchain, Internet of Things, and 5G) offers transformative ...
Goddy Uwa Osimen +5 more
wiley +1 more source
mLife, Volume 4, Issue 6, Page 664-680, December 2025.Abstract Influenza A viruses (IAVs) pose a significant threat to global health, causing annual epidemics and occasional pandemics with substantial morbidity and mortality. Despite the availability of vaccines and antiviral therapies, the development of novel preventive and therapeutic strategies remains a critical research focus.
Di Wang +7 more
wiley +1 more source