Results 1 to 10 of about 441,587 (213)

Class I/Class II HLA Evolutionary Divergence Ratio Is an Independent Marker Associated With Disease-Free and Overall Survival After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia

Frontiers in Immunology, 2022
Class I Human Leukocyte Antigen (HLA) evolutionary divergence (HED) is a metric which reflects immunopeptidome diversity and has been associated with immune checkpoint inhibitor responses in solid tumors.
Anne-Marie Daull, Valérie Dubois, Hélène Labussière-Wallet, Fabienne Venet, Fabienne Venet, Fiorenza Barraco, Sophie Ducastelle-Lepretre, Marie-Virginie Larcher, Marie Balsat, Lila Gilis, Gaëlle Fossard, Hervé Ghesquières, Maël Heiblig, Maël Heiblig, Florence Ader, Florence Ader, Florence Ader, Vincent Alcazer, Vincent Alcazer   +18 more
doaj   +1 more source

Genetic variant of SPARC gene and its association with growth traits in Chinese cattle [PDF]

Archives Animal Breeding, 2020
SPARC is a cysteine-rich acidic secreted protein. It is a non-collagen component of bone, which is widely distributed in humans and animals and plays an important role.
D. Zhang, J. Xu, P. Yang, Y. Wen, H. He, H. He, J. Li, J. Liang, Y. Zheng, Z. Zhang, X. Wang, X. Yu, E. Wang, C. Lei, H. Chen, Y. Huang   +15 more
doaj   +1 more source

Genetic Diversity of HLA Class I and Class II Alleles in Thai Populations: Contribution to Genotype-Guided Therapeutics

Frontiers in Pharmacology, 2020
Human leukocyte antigen (HLA) class I and II are known to have association with severe cutaneous adverse reactions (SCARs) when exposing to certain drug treatment. Due to genetic differences at population level, drug hypersensitivity reactions are varied,
Patompong Satapornpong, Patompong Satapornpong, Patompong Satapornpong, Pimonpan Jinda, Pimonpan Jinda, Thawinee Jantararoungtong, Thawinee Jantararoungtong, Napatrupron Koomdee, Napatrupron Koomdee, Chonlawat Chaichan, Chonlawat Chaichan, Jirawat Pratoomwun, Jirawat Pratoomwun, Chalitpon Na Nakorn, Wichai Aekplakorn, Alisa Wilantho, Alisa Wilantho, Chumpol Ngamphiw, Chumpol Ngamphiw, Sissades Tongsima, Sissades Tongsima, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem   +23 more
doaj   +1 more source

Joint latent class model: Simulation study of model properties and application to amyotrophic lateral sclerosis disease

BMC Medical Research Methodology, 2021
Background In many clinical applications, evolution of a longitudinal marker is censored by an event occurrence, and, symmetrically, event occurrence can be influenced by the longitudinal marker evolution.
Maéva Kyheng, Génia Babykina, Camille Ternynck, David Devos, Julien Labreuche, Alain Duhamel   +5 more
doaj   +1 more source

Expression of class III beta-tubulin in malignant epithelial tumours: an immunohistochemical study using TU-20 and TuJ-1 antibodies.

Folia Histochemica et Cytobiologica, 2007
Class III beta-tubulin has been discovered as a marker of early phases of neuronal differentiation in developmental conditions, as well as in different tumours of neuronal origin.
Eva PĂ­sarĂ­ kovĂĄ, TomĂĄs JirĂĄsek, VladimĂ­r ViklickĂ˝, VĂĄclav Mandys   +3 more
doaj   +1 more source

New breeding tools impact Canadian commercial farmer fields

Czech Journal of Genetics and Plant Breeding, 2011
The high cost of cultivar development encourages efficiencies to reduce time and costs to develop cultivars. Doubled haploid (DH) technology and marker assisted breeding (MAB) are two such tools that improve efficiencies.
R.M. DePAUW, R.E. KNOX, D.G. HUMPHREYS, J.B. THOMAS, S.L. FOX, P.D. BROWN, A.K. SINGH, C. POZNIAK, H.S. RANDHAWA, D.B. FOWLER, R.J. GRAF, P. HUCL   +11 more
doaj   +1 more source

Expression of GFP-mTalin reveals an actin-related role for the Arabidopsis Class II formin AtFH12

Biologia Plantarum, 2012
Formins (FH2 proteins) are implicated in F-actin nucleation and other aspects of cytoskeletal organization. Plants possess two formin clades, relatively well-described Class I formins and so far poorly characterized Class II formins.
F. Cvrčková, M. Grunt, V. Žárský
doaj   +1 more source

Diagnostic significance of the novel biomarker combination for early-stage non-small cell lung cancer detection: results of the blind clinical study

Frontiers in Oncology
BackgroundNSCLC can be cured in up to 65% of cases if detected early. However, most of the lung cancer (LC) cases are diagnosed at an advanced stage.ObjectiveThe assessment of various tumor markers in retrospective double-blind clinical study and their ...
Janneta Tcherkassova, Evgueni Klinski, Sergey Tsurkan, Anna Prostyakova, Alexander Boroda, Yuliya N. Pirogova, Leonid N. Bagmet, Marina Sekacheva   +7 more
doaj   +1 more source

Diagnostic accuracy and prediction increment of markers of epithelial-mesenchymal transition to assess cancer cell detachment from primary tumors

BMC Cancer, 2018
Background Metastases play a role in about 90% of cancer deaths. Markers of epithelial-mesenchymal transition (EMT) measured in primary tumor cancer cells might provide diagnostic information about the likelihood that cancer cells have detached from the ...
Evan L. Busch, Prabhani Kuruppumullage Don, Haitao Chu, David B. Richardson, Temitope O. Keku, David A. Eberhard, Christy L. Avery, Robert S. Sandler   +7 more
doaj   +1 more source

Comparative Genomic Analysis of the Class Epsilonproteobacteria and Proposed Reclassification to Epsilonbacteraeota (phyl. nov.)

Frontiers in Microbiology, 2017
The Epsilonproteobacteria is the fifth validly described class of the phylum Proteobacteria, known primarily for clinical relevance and for chemolithotrophy in various terrestrial and marine environments, including deep-sea hydrothermal vents.
Philip Hugenholtz, David W. Waite, Inka Vanwonterghem, Christian Rinke, Donovan H. Parks, Ying Zhang, Ken Takai, Stefan M. Sievert, Jörg Simon, Barbara J. Campbell, Thomas E. Hanson, Tanja Woyke, Martin G. Klotz, Martin G. Klotz   +13 more
doaj   +1 more source