The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Militar/Scientific Skills Vinicius Numbersヴィニシウスの数字 7 knowledge Areas: Theology Health Arts Languages Management Cultures Technology Courses: 1: Theology/2017 To 2025 2: Militar Training/2019 To 2025 3: Scientific Training/2010 To 2025 4 ...
Vinicius Numbers
core +1 more source
On a class of graphs with equal domination and certified domination numbers [PDF]
Discrete Mathematics LettersMateusz Miotk
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Enhancing detection of polygenic adaptation: a comparative study of machine learning and statistical approaches using simulated evolve-and-resequence data. [PDF]
BMC GenomicsCaliendo C, Gerber S, Pfenninger M.
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
30 year class book : Class of 1906.
, 1936 30 year class book, Class of 1906, Lehigh University. Pottstown, (Pa.) : The Feroe press 1936. 90 p. : ill., port.
core
Classification of Adolescent Drinking via Behavioral, Biological and Environmental Variables: A Machine Learning Approach With Bias Control. [PDF]
Addict BiolLiu R +5 more
europepmc +1 more source