Results 101 to 110 of about 1,458,495 (316)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A novel graphical and analytical method for the kinematic analysis of fourth class Assur groups

Revista Facultad de Ingeniería Universidad de Antioquia, 2012
A method for the kinematic analysis of a fourth class Assur group, using a combination of graphical and analytical methods, is presented in this paper. The solution is obtained through a method in which two special Assur points are used.
Héctor Quintero, Gabriel Calle, Alexander Díaz, Edison Henao   +3 more
doaj   +1 more source

On conjugacy separability of some Coxeter groups and parabolic-preserving automorphisms

, 2013
We prove that even Coxeter groups, whose Coxeter diagrams contain no (4, 4, 2) triangles, are conjugacy separable. In particular, this applies to all right-angled Coxeter groups or word hyperbolic even Coxeter groups. For an arbitrary Coxeter group W, we
Caprace, Pierre-Emmanuel, Minasyan, Ashot   +1 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Generation of proper classes of short exact sequences

International Journal of Mathematics and Mathematical Sciences, 1997
The generation of proper classes of short exact sequences of modules by subclasses is considered. The class generated by two proper classes is studied by means of some operations between these classes.
Ali Pancar
doaj   +1 more source

Centralisers of finite subgroups in soluble groups of type FPn

, 2009
We show that for soluble groups of type FPn , centralisers of finite subgroups need not be of type ...
Martínez-Pérez, Conchita, Nucinkis, Brita E.A., Martinez-Perez, C, Kochloukova, Dessislava H., Kochloukova, DH, Nucinkis, BEA   +5 more
core   +1 more source

'Oh goodness, I am watching reality TV': How methods make class in audience research [PDF]

, 2008
One of the most striking challenges encountered during the empirical stages of our audience research project, `Making Class and the Self through Televised Ethical Scenarios' (funded as part of the ESRC's Identities and Social Action programme), stemmed ...
Skeggs, Bev, Wood, Helen, Bev Skeggs, Nancy Thumim, Thumim, Nancy, Skeggs, B., Helen Wood, Thumim, N.   +7 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source