Results 251 to 260 of about 312,758 (315)

Experimental Study on Physical Simulation of Different Development Methods for Horizontal Wells in Heterogeneous Conglomerate Reservoirs. [PDF]

ACS Omega
Wang X, Liu D, Zhou Y, Dong H, Qian C, Zhang C.   +5 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

TiCl₃-Mediated Reductive Aminohydroxylation of Alkenes to (Benzo)Furo[3,2-<i>b</i>]Indolines. [PDF]

Org Lett
Boyarskaya D, Gri P, Delayre B, Wang Q, Zhu J.   +4 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Rh(iii)-catalyzed oxidative C-H annulation of 6-arylpyridazin-3(2<i>H</i>)-ones: direct access to diarylpyridazino[6,1-<i>a</i>]isoquinolin-5-ium-3-olates. [PDF]

RSC Adv
Ittamalla C, Mukundram NSS, Nagireddy J, Sridhar B, Reddy BVS.   +4 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Tetra-substituted BDPA radicals <i>via</i> click-chemistry and application to liquid-state DNP.

Chem Commun (Camb)
Ahmad IM, Roy P, Kuzhelev A, Sigurdsson ST.   +3 more
europepmc   +1 more source

A Rh(II) Catalyzed Atropisomer Selective Ring Expansion of 3-Aryl Indoles to 4-Aryl Quinolines. [PDF]

ACS Catal
Basilaia M, Zanolini R, Dogan NK, Rustin G, Regganie T, Susskind NJ, Gustafson J, Mao Y.   +7 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source