Results 61 to 70 of about 1,320,086 (216)
Modeling Class Size Effects Across the Achievement Distribution
Previous findings from Project STAR have highlighted the benefits of being in small classes in early grades on average. Here, we examined the differential “value-added” effects of small classes across the achievement distribution.
Spyros Konstantopoulos, Wei Li
doaj +1 more source
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Inquiry Learning: Level, Discipline, Class Size, What Matters?
Inquiry learning is a pedagogical approach that focuses on the processes and skills required to conduct research. It is a pedagogical approach that has been demonstrated to have positive learning outcomes.
Susan Vajoczki +3 more
doaj +1 more source
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
NET COSTS OF CLASS-SIZE REDUCTION: THE PORTUGUESE CASE [PDF]
This article aims to promote further reflection on the benefits derived from class-size reduction, seeking to demonstrate that the expenditures resulting from this are usually overestimated when they are determined on the basis of gross employee cost to ...
Pedro Ribeiro Mucharreira +2 more
doaj +3 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Obligate faunivorous megatheropod size class patterns across the Jurassic-Cretaceous Periods [PDF]
Allosauroidea, Ceratosauria, Megalosauroidea, Megaraptora, and Tyrannosauroidea are five clades containing obligate faunivorous megatheropods. These clades included apex predators from the Early Jurassic until the end of the Cretaceous Period.
Colin Boisvert +5 more
doaj +2 more sources

