Results 91 to 100 of about 10,543,759 (362)

Migração e diferenciação de classes na Guiné-Bissau rural

e-cadernos ces, 2012
Este artigo apresenta alguns dos resultados de um projeto de investigação sobre migrações e desenvolvimento na Guiné-Bissau, no qual “desenvolvimento” é entendido como um processo conflitual e geograficamente diferenciado de recomposição socioeconómica ...
Alexandre Abreu
doaj   +1 more source

Classes of decision analysis [PDF]

, 2016
The ultimate task of an engineer consists of developing a consistent decision procedure for the planning, design, construction and use and management of a project.
Caspeele, Robby, Val, Dimitri, Xing, Cheng   +2 more
core   +1 more source

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source

Intuition and Russell´s Paradox

Principia: An International Journal of Epistemology, 2001
In this essay I will examine the role that intuition plays in Russell's paradox; showing how different approaches to intuition will license different treatments of the paradox.
Margaret Cuonzo
doaj  

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Detalhamento das classes solos da Bacia hidrográfica do Riacho do Tigre

Revista de Geociências do Nordeste, 2016
Este trabalho teve por objetivo contribuir para o aumento na precisão do mapeamento de solos com o detalhamento de escala. A área de estudo corresponde a Bacia do Riacho Tigre que está localizada no município de São João do Tigre-PB.
Stéphanie Medeiros Lima, Jonas Otaviano Praça Souza   +1 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Probabilistic Inductive Classes of Graphs

, 2006
Models of complex networks are generally defined as graph stochastic processes in which edges and vertices are added or deleted over time to simulate the evolution of networks.
Curry H. B., Diestel R., Doreian P., Eberhard V., Graham R. L., Khanafiah D., Lovasz L., Moore C., NATAŠA KEJŽAR, Roberts F. S., VLADIMIR BATAGELJ, Wang Z., White D. R., Wilensky U., ZORAN NIKOLOSKI   +14 more
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source