Results 101 to 110 of about 7,126,971 (323)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Transgenic wheat expressing a barley class II chitinase gene has enhanced resistance against Fusarium graminearum [PDF]

open access: bronze, 2008
S. Shin   +8 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

The Human Being's Role in the Process of Epistemological Effectiveness of the Social Factors [PDF]

open access: yesIslām va ̒ulūm-i ijtimā̒ī
The human being is a social creature whose perfections grow in the context of sociallife and that is why he/she deals with the social factors continually.
Ghodratollah Ghorbani
doaj  

EVALUATION AND COMPARISON OF GROUNDWATER VULNERABILITY TO POLLUTION BY THE DRASTIC AND GOD METHODS: A CASE OF WADI NIL ALLUVIAL PLAIN (JIJEL, NE ALGERIA)

open access: yesFood and Environment Safety, 2022
The current research aims to compare the results of two vulnerability estimation methods (DRASTIC and GOD) in superficial and deep aquifer of Wadi Nil alluvial plain (NE Algerian).
Souhil MAHDID   +5 more
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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