Trajectories of cigarette smoking and exposure to welding fumes and their impact on lung cancer risks: a latent class modelling approach. [PDF]
Kendzia B +7 more
europepmc +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
A distinct class of peas (Pisum sativum L.) from Afghanistan that show strain specificity for symbiotic Rhizobium [PDF]
J. Peter W. Young, P. Matthews
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Soil multifunctionality and temporal variability of nutrients across vigor classes in wild apple trees (<i>Malus sieversii</i>). [PDF]
Gu CQ +5 more
europepmc +1 more source
Entanglement classes of permutation-symmetric qudit states: Symmetric operations suffice [PDF]
Piotr Migdał +2 more
openalex +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Patterns of alcohol use and response to digital brief interventions in college students: a secondary analysis of a cluster randomized trial. [PDF]
Ghosh A +8 more
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Impact of moral education on anomie behaviors in university students' physical education classes: serial mediation of attitudes toward sports norms and self-efficacy. [PDF]
Liu L +5 more
europepmc +1 more source

