Results 171 to 180 of about 10,543,759 (362)

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

Categories, Classes and Identities in Time. Escaping Chronocentric Modernity

Práticas da História, 2018
In this article I will mainly explore some questions related to the ways in which historians and other social scientists usually identify, distinguish and classify people from the past, grouping them according to different criteria: economic ...
Javier Fernández-Sebástian
doaj  

A Study of Individual Chromosome Composition of the Various Chromosome-number Classes at Pollen-mitosis I in a Triploid Plant

, 1959
J. Yanney Wilson
openalex   +2 more sources

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

A NEW CLASS OF PHTHALEINS—MIXED PHTHALEINS—FORMED BY HEATING p-HYDROXYBENZOYL-o-BENZOIC ACID WITH PHENOLS. [PDF]

, 1917
W. R. Orndorff, Miss R. R. Murray
openalex   +1 more source

The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes

Nature, 2003
H. Skaletsky, Tomoko Kuroda-Kawaguchi, P. Minx, Holland S. Cordum, L. Hillier, L. Brown, S. Repping, Tatyana Pyntikova, Johar Ali, Tamberlyn Bieri, A. Chinwalla, A. Delehaunty, K. Delehaunty, H. Du, Ginger A. Fewell, L. Fulton, R. Fulton, Tina Graves, Shunfeng Hou, Philip Latrielle, S. Leonard, E. Mardis, Rachel Maupin, J. McPherson, T. Miner, W. Nash, Christine Nguyen, P. Ozersky, K. Pepin, S. Rock, T. Rohlfing, Kelsi Scott, Brian Schultz, C. Strong, A. Tin-Wollam, Shiaw-Pyng Yang, R. Waterston, R. Wilson, S. Rozen, D. Page   +39 more
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Optimization, approximation, and complexity classes

Symposium on the Theory of Computing, 1991
C. Papadimitriou, M. Yannakakis
semanticscholar   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

Retraction: Molecular structure and dimeric organization of the Notch extracellular domain as revealed by electron microscopy. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source