Results 151 to 160 of about 235,773 (256)

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

open access: yesAdvanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li   +5 more
wiley   +1 more source

Accelerated recovery using magnesium ibogaine: characterizing the subjective experience of its rapid healing from neuropsychiatric disorders. [PDF]

open access: yesNpj Ment Health Res
Olash C   +8 more
europepmc   +1 more source

AutomataGPT: Transformer‐Based Forecasting and Ruleset Inference for Two‐Dimensional Cellular Automata

open access: yesAdvanced Science, EarlyView.
We introduce AutomataGPT, a generative pretrained transformer (GPT) trained on synthetic spatiotemporal data from 2D cellular automata to learn symbolic rules. Demonstrating strong performance on both forward and inverse tasks, AutomataGPT establishes a scalable, domain‐agnostic framework for interpretable modeling, paving the way for future ...
Jaime A. Berkovich   +2 more
wiley   +1 more source

Doing Classic Grounded Theory with Quantitative Data

open access: yesGrounded Theory Review: An International Journal
Generally, when researchers think of one type of data associated with classic grounded theory, most probably qualitative data that comes to mind. While a researcher may, indeed, use qualitative data with classic grounded theory, there is a possible ...
Barry Chametzky
doaj  

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

open access: yesAdvanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su   +10 more
wiley   +1 more source

Editorial: Theory of mind in robots and intelligent systems. [PDF]

open access: yesFront Robot AI
Gurney N, Hughes D, Pynadath DV, Wang N.
europepmc   +1 more source

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

open access: yesAdvanced Science, EarlyView.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang   +15 more
wiley   +1 more source

Glaserian Classic Grounded Theory and Descriptive Phenomenology

open access: yesGrounded Theory Review: An International Journal
Though one may presume that all qualitative designs are similar—and to a certain degree, they are, there are some similarities and differences in two designs—phenomenology and Glaserian classic grounded theory—which need to be explored in a more nuanced
Barry Chametzky
doaj  

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