Commentary: One mechanism of Sishen Pill on diarrhea with kidney Yang deficiency syndrome: influencing metabolic function by intestinal microorganisms and enzyme activity mediates the gut-kidney axis. [PDF]
Yao J, Lin J, Xv Y.
europepmc +1 more source
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Predicting Low-Cycle Fatigue Life Using New Energy-Based Fatigue Damage Measures. [PDF]
Mroziński S +3 more
europepmc +1 more source
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang +5 more
wiley +1 more source
From depletion to distress: identifying the nonlinear relationship and core intervention target through computational simulation modelling between compassion fatigue and moral distress among ICU nurses: a cross-sectional study. [PDF]
Zheng X, Zhu X, Wang A.
europepmc +1 more source
SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He +5 more
wiley +1 more source
An Intuitive Approach to the Optimal Sampling of an Electromagnetic Field. [PDF]
Migliore MD.
europepmc +1 more source
A key challenge in nicotine electroanalysis is the unresolved complexity of its interface process, which directly determines sensor metrics. Herein, the proton‐coupled electron transfer mechanism of nicotine is decoded for multi‐scenario portable electrochemical sensing.
Yi Peng +9 more
wiley +1 more source
Recognising and alleviating unbearable suffering in residents living in Swiss nursing homes: a grounded theory study on nursing staff's perspectives on sedating medications and palliative sedation. [PDF]
Monteverde M +5 more
europepmc +1 more source

