Results 121 to 130 of about 6,056,592 (368)
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
THE ROLE OF RATIONALITY PHILOSOPHY IN LEGAL STUDIES (PART II)
The relevance of the article, which consists of two parts, is that the various theories of rationality presented only in philosophical works are considered.
Valeriy P. Ivanskiy, Sergey I. Kovalev
doaj +1 more source
Classical Extensions, Classical Representations and Bayesian Updating in Quantum Mechanics
I review the formalism of classical extensions of quantum mechanics introduced by Beltrametti and Bugajski, and compare it to the classical representations discussed e.g.
Bacciagaluppi, Guido
core +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Vibrio cholerae Pathogenic Clones
We resolved the relationships between 2 pandemic clones of Vibrio cholerae. Using 26 housekeeping genes, we showed that the US Gulf clone, the Australian clone, and 3 El Tor strains isolated before the seventh pandemic were related to the seventh ...
Anna Salim, Ruiting Lan, Peter R. Reeves
doaj +1 more source
Relative Applicability of the Classical and the Balance Hypotheses to Man. Especially with Respect to Quantitative Characters [PDF]
Makoto Kimura
openalex +1 more source
Methane Concentration Prediction Method Based on Deep Learning and Classical Time Series Analysis [PDF]
Xiangrui Meng +2 more
openalex +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
This report presents the results of surveillance on transmissible spongiform encephalopathies in cattle, sheep, goats, cervids and other species, and genotyping in sheep and goats, carried out in 2023 by 27 Member States (MS, EU27), the United Kingdom ...
European Food Safety Authority (EFSA)
doaj +1 more source
Characterizing the transition from classical to quantum as an irreversible loss of physical information [PDF]
Philippe Guillemant +2 more
openalex +1 more source

