Results 131 to 140 of about 2,227,052 (304)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
File 2: Correspondence, 1967-1975 [PDF]
, 1975 Lakeside Orchards Improvement District correspondence, 1967-1975.
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Holographic renormalization of Horndeski gravity
Journal of High Energy PhysicsWe study the renormalization of a particular sector of Horndeski theory. In particular, we focus on the nonminimal coupling of a scalar field to the Gauss-Bonnet term and its kinetic coupling to the Einstein tensor.
Nicolás Cáceres +3 more
doaj +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Asymptotic analysis of energy functionals in anti-de Sitter spacetimes
Journal of High Energy PhysicsConformal Gravity (CG) is a Weyl-invariant metric theory whose action is free from divergences for generic asymptotically anti-de Sitter spaces. For Neumann boundary conditions, it reduces to renormalized Einstein-AdS gravity at tree level. By evaluating
Giorgos Anastasiou +2 more
doaj +1 more source
Transient chaos - a resolution of breakdown of quantum-classical correspondence in optomechanics. [PDF]
Sci Rep, 2016 Wang G, Lai YC, Grebogi C.
europepmc +1 more source
, 2000 This paper is an essay review of Steven French and Harmke Kamminga (eds.), Correspondence, Invariance and Heuristics. Essays in Honour of Heinz Post (Dordrecht: Kluwer, 1993). I distinguish a varity of correspondence relations between scientific theories
Hartmann, Stephan
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Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Are S 1 × S 2 wormholes generic with large sources?
Journal of High Energy PhysicsEuclidean path integrals can be used to prepare states of a Lorentzian QFT. So long as any sources are turned off on the t = 0 surface, the resulting Lorentzian states all belong to the same Hilbert space.
Xiaoyi Liu +2 more
doaj +1 more source