Results 81 to 90 of about 2,227,052 (304)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Decoherence in a classically chaotic quantum system: Entropy production and quantum-classical correspondence [PDF]

open access: yesPhysical Review E, 2001
We study the decoherence process for an open quantum system which is classically chaotic (a quartic double well with harmonic driving coupled to a sea of harmonic oscillators). We analyze the time dependence of the rate of entropy production showing that it has two relevant regimes: For short times it is proportional to the diffusion coefficient (fixed
Monteoliva, Diana, Paz, Juan Pablo
openaire   +4 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Quantum–classical correspondence in spin–boson equilibrium states at arbitrary coupling

open access: yesNew Journal of Physics
The equilibrium properties of nanoscale systems can deviate significantly from standard thermodynamics due to their coupling to an environment. We investigate this here for the θ -angled spin–boson model, where we first derive a compact and general form ...
F Cerisola   +5 more
doaj   +1 more source

Flat entanglement spectra in fixed-area states of quantum gravity

open access: yesJournal of High Energy Physics, 2019
We use the Einstein-Hilbert gravitational path integral to investigate gravita- tional entanglement at leading order O(1/G). We argue that semiclassical states prepared by a Euclidean path integral have the property that projecting them onto a subspace ...
Xi Dong, Daniel Harlow, Donald Marolf
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Superselection sectors of gravitational subregions

open access: yesJournal of High Energy Physics, 2019
Motivated by the problem of defining the entanglement entropy of the graviton, we study the division of the phase space of general relativity across subregions.
Joan Camps
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Einstein-AdS action, renormalized volume/area and holographic Rényi entropies

open access: yesJournal of High Energy Physics, 2018
We exhibit the equivalence between the renormalized volume of asymptotically anti-de Sitter (AAdS) Einstein manifolds in four and six dimensions, and their renormalized Euclidean bulk gravity actions.
Giorgos Anastasiou   +3 more
doaj   +1 more source

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