Results 51 to 60 of about 1,142 (91)

Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer's disease in cerebrospinal fluid. [PDF]

Alzheimers Res Ther
Hou X, Qiu Y, Li H, Yan Y, Zhao D, Ji S, Ni J, Zhang J, Liu K, Qing H, Quan Z.   +10 more
europepmc   +1 more source

Single-cell epigenomics uncovers heterochromatin instability and transcription factor dysfunction during mouse brain aging. [PDF]

Cell Rep
Amaral ML, Mamde S, Miller M, Hou X, Arzavala J, Osteen J, Johnson ND, Smoot EW, Yang Q, Eisner E, Zeng Q, Báez-Becerra CT, Olness J, Kern JC, Rink J, Barcoma A, Cho S, Cao S, Emerson N, Lee J, Willier J, Loe T, Jiao H, Zu S, Zhu Q, Preissl S, Wang A, Ecker JR, Behrens MM, Ren B.   +29 more
europepmc   +1 more source

Recreating viable YY^h genotype uncovers the role of CpYYL underlying YY lethality in papaya. [PDF]

Nat Commun
Yue J, Liu J, Zeng Q, Wai CM, Deng B, Tong Y, Zuo L, Xiang T, Xie W, Zhao X, Lai J, Liao J, Lai Q, Xu L, Zhu Y, He J, Zhang M, Nie S, Lin Z, Liang Y, Jiang S, Chen X, Wang B, Huang Y, Xu Y, Nguyen-Edquilang J, Ma Y, Fumia N, Jones T, Quesada-Rojas P, Mora-Newcomer E, Zhang J, Yu Q, Wang ML, Ming R.   +34 more
europepmc   +1 more source

Deep learning prioritizes cancer mutations that alter protein nucleocytoplasmic shuttling to drive tumorigenesis. [PDF]

Nat Commun
Zheng Y, Yu K, Lin JF, Liang Z, Zhang Q, Li J, Wu QN, He CY, Lin M, Zhao Q, Zuo ZX, Ju HQ, Xu RH, Liu ZX.   +13 more
europepmc   +1 more source

Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma. [PDF]

Nat Commun
Yang J, Wang C, Fu D, Ho LL, Galani K, Chen L, Gonzalez J, Fu J, Huang AY, Frederick DT, He L, Asnani M, Tacke R, Robitschek EJ, Yadav SK, Deng W, Burke KP, Sharova T, Sullivan RJ, Weiss S, Rai K, Liu D, Boland GM, Kellis M.   +23 more
europepmc   +1 more source

TNF alpha unmasks enteric malate aspartate shuttle dysfunction bridging Parkinson disease and intestinal inflammation. [PDF]

Nat Commun
Ghirotto B, Gonçalves LE, Ruder V, James C, Gerasimova E, Rizo T, Wend H, Farrell M, Gerez JA, Prymaczok NC, Kuijs M, Shulman M, Hartebrodt A, Prots I, Gessner A, Vieth M, Zunke F, Winkler J, Blumenthal DB, Theis FJ, Riek R, Günther C, Neurath M, Gupta P, Winner B.   +24 more
europepmc   +1 more source

BMP-Smad1/9 signaling plays a critical role in regulating zebrafish PGC proliferation. [PDF]

Nat Commun
Zheng T, Li Y, Li G, Wei Z, Li J, Jiang Z, Shah R, Zhang W, Xing C, Meng A, Wu X.   +10 more
europepmc   +1 more source

Atherosclerotic Fibrous Plaques in Women Present ECM Remodeling Linked to TGF-β. [PDF]

Circ Res
Sakkers TR, Mili E, Winter H, Kapteijn D, Perry RN, Barbera N, Watts K, Dias IR, Meteva D, Wesseling M, Mol BM, de Borst GJ, de Kleijn DPV, van der Laan SW, Civelek M, White SJ, Maegdefessel L, Mayr M, Pasterkamp G, Mokry M, Benavente ED, den Ruijter HM.   +21 more
europepmc   +1 more source

The Alzheimer's therapeutic Lecanemab attenuates Aβ pathology by inducing an amyloid-clearing program in microglia. [PDF]

Nat Neurosci
Albertini G, Zielonka M, Cuypers ML, Snellinx A, Xu C, Poovathingal S, Wojno M, Davie K, van Lieshout V, Craessaerts K, Wolfs L, Pasciuto E, Jaspers T, Horré K, Serneels L, Fiers M, Dewilde M, De Strooper B.   +17 more
europepmc   +1 more source

IAPEz retrotransposons regulate the first lineage segregation in mouse pre-implantation development. [PDF]

Nucleic Acids Res
Huang R, Han Z, Liufu Z, Quan X, Li D, Dong H, Hong G, Chen R, Zhang M, Peng G, Pei D, Chen J, He J.   +12 more
europepmc   +1 more source