Results 71 to 80 of about 1,142,466 (290)

A Theory of Entanglement

Quanta, 2020
This article presents the basis of a theory of entanglement. We begin with a classical theory of entangled discrete measures. Then, we treat quantum mechanics and discuss the statistics of bounded operators on a Hilbert space in terms of context ...
Stan Gudder
doaj   +1 more source

IR finite graviton propagators in de Sitter spacetime

, 2016
Graviton propagator diverges in certain gauges in de Sitter spacetime. We address this problem in this work by generalizing the infinitesimal BRST transformations in de Sitter spacetime to finite field-dependent BRST (FFBRST) transformations.
Faizal, Mir, Mandal, Bhabani Prasad, Upadhyay, Sudhaker   +2 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Properties on measure pseudo almost automorphic functions and applications to fractional differential equations in Banach spaces

Electronic Journal of Differential Equations, 2018
In this article, we establish some new composition theorems on measure pseudo almost automorphic functions via measure theory. The obtained compositions theorems generalize those established under the well-known Lipschitz conditions or the classical ...
Yong-Kui Chang, Tian-Wei Feng
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The information metric on the moduli space of instantons with global symmetries

Physics Letters B, 2016
In this note we revisit Hitchin's prescription [1] of the Fisher metric as a natural measure on the moduli space of instantons that encodes the space–time symmetries of a classical field theory. Motivated by the idea of the moduli space of supersymmetric
Emanuel Malek, Jeff Murugan, Jonathan P. Shock   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Modeling and Fusing the Uncertainty of FMEA Experts Using an Entropy-Like Measure with an Application in Fault Evaluation of Aircraft Turbine Rotor Blades

Entropy, 2018
As a typical tool of risk analysis in practical engineering, failure mode and effects analysis (FMEA) theory is a well known method for risk prediction and prevention.
Xuelian Zhou, Yongchuan Tang
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

The Test of Practice–An Essay

Education Sciences, 2017
This essay starts in medias res, in the puzzling reappearance of the classical metaphor of Bildung as the transformation of man’s “first” animal nature into the “second” cultivated one. I call it the two-natures metaphor.
Lars Løvlie
doaj   +1 more source