Results 81 to 90 of about 1,144,514 (290)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Lévy laplacians and annihilation process
Учёные записки Казанского университета: Серия Физико-математические науки, 2018 The Lévy Laplacians are infinite-dimensional Laplace operators defined as the Cesaro mean of the second-order directional derivatives. In the theory of Sobolev–Schwarz distributions over a Gaussian measure on an infinite-dimensional space (the Hida ...
B.O. Volkov
doaj
Detecting Signatures of Criticality Using Divergence Rate
EntropyOftentimes in a complex system it is observed that as a control parameter is varied, there are certain intervals during which the system undergoes dramatic change.
Tenzin Chan +2 more
doaj +1 more source
A Classical Density-Functional Theory for Describing Water Interfaces
, 2012 We develop a classical density functional for water which combines the White Bear fundamental-measure theory (FMT) functional for the hard sphere fluid with attractive interactions based on the Statistical Associating Fluid Theory (SAFT-VR).
Alberts B. +6 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Quantum systems as classical systems
, 2001 A characteristical property of a classical physical theory is that the observables are real functions taking an exact outcome on every (pure) state; in a quantum theory, at the contrary, a given observable on a given state can take several values with ...
Antonio Cassa, Jauch J. M.
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
KARŞILAŞTIRMALI OLASILIK: NİTELİKSEL/BAĞINTISAL/SEZGİSEL BİR OLASILIK KAVRAMI
Felsefe Dünyası, 2002 Since probabilistic interpretation of the universe in Quantum physics has take: place of deterministic interpretation of it in the classical Newtonian physics, probability has become a more important concept in science and thereby in philosophy of ...
Zekiye Kutlusoy
doaj
Sharp and fuzzy observables on effect algebras
, 2007 Observables on effect algebras and their fuzzy versions obtained by means of confidence measures (Markov kernels) are studied. It is shown that, on effect algebras with the (E)-property, given an observable and a confidence measure, there exists a fuzzy ...
A. Dvurečenskij +31 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source